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Akcier Skuamoz Hcreli Karsinomunda Hipofiz Metastaz [Respir Case Rep]
Respir Case Rep. 2019; 8(2): 62-66 | DOI: 10.5505/respircase.2019.05945

Akcier Skuamoz Hcreli Karsinomunda Hipofiz Metastaz

Fatma Tokgoz Akyil1, Emre Sedar SAYGILI2, Belgit Talay3, Mustafa Akyl4
1anakkale Mehmet Akif Ersoy Devlet Hastanesi, Gs Hasta-lklar Blm, anakkale
2anakkale Mehmet Akif Ersoy Devlet Hastanesi, Endokrinoloji Blm, anakkale
3anakkale Mehmet Akif Ersoy Devlet Hastanesi, Nkleer Tp Blm, anakkale
4anakkale Mehmet Akif Ersoy Devlet Hastanesi, Gs Cerrahisi Blm, anakkale

Hipofiz metastazlar asemptomatik olabilen, grntlemelerde kolayca gzden kaabilen ve ok nadir grlen metastazlardr. Bu olgu sunumunda, asemptomatik hipofiz metastaz saptanan akcier skuamoz hcreli karsinomu tans konulan bir erkek hasta sunulmutur. Yetmi yanda erkek hasta, genel durum bozukluu nedeniyle ekilen toraks bilgisayarl tomografide sa alt lobda kitle tespit edilerek kliniimize ynlendirildi. Bronkoskopide sa ara bronta izlenen lezyondan yaplan biyopsi skuamoz hcreli karsinom ile uyumluydu. Pozitron emisyon tomografi grntlemede akcier kitlesi, mediastinal lenfadenopatiler, karacier ve yaygn kemik metastazlarnn yannda hipofiz sol kesiminde artm metabolik aktivite izlendi. Hastann hormon paneli hiperprolaktinemi ve hipogonadotropik hipogonadizm ile uyumluydu. Hipofiz manyetik rezonans grntleme infundibulum deviasyonu ve optik kiazma indentasyonu yapan 18x12 mm lezyon saptand. Bu bulgularla hipofiz metastaz tans konulan hastaya radyoterapi planland fakat hasta tedavi alamayarak eksitus oldu. Akcier kanserinde hipofiz bezi metastaz nadir de olsa grlebilir. Yalnz grntleme bulgularnda saptanabilir veya takiplerde spesifik semptomlarla karmza kabilir.

Anahtar Kelimeler: akcier kanseri, hiperprolaktinemi, hipofiz metastaz

Pituitary Metastasis in Squamous Cell Lung Carcinoma

Fatma Tokgoz Akyil1, Emre Sedar SAYGILI2, Belgit Talay3, Mustafa Akyl4
1Department of Chest Diseases, Canakkale Mehmet Akif Ersoy State Hospital, anakkale, Turkey
2Department of Endocrinology, Canakkale Mehmet Akif Ersoy State Hospital, anakkale, Turkey
3Department of Nuclear Medicine, Canakkale Mehmet Akif Ersoy State Hospital, anakkale, Turkey
4Department of Thoracic Surgery, Canakkale Mehmet Akif Ersoy State Hospital, anakkale, Turkey

Metastases to the pituitary gland are extremely rare, and can be asymptomatic and easily overlooked in imaging. In this case report, a male patient diagnosed with a lung squamous cell carcinoma with asymptomatic pituitary metastasis is presented. A 70-year-old man was referred to our clinic with a right lower lobe mass identified in a thorax computed tomography. A bronchoscopic biopsy from the intermediate bronchus revealed a squamous cell carcinoma. Positron emission tomography imaging revealed increased metabolic activity in the lung mass; multiple mediastinal lymphadenopathies; liver and diffuse bone lesions along the left side of the pituitary gland. The patient's hormone panel was consistent with hyperprolactinemia and hypogonadotropic hypogonadism. Pituitary magnetic resonance imaging detected a deviation in the infundibulum and optic chiasm indentation with an 18 x 12 mm mass lesion. The patient was diagnosed with pituitary metastasis and radiotherapy was planned. The patient was unable to attend the follow-up and died within one month of diagnosis. Pituitary gland metastasis is extremely rare in lung cancer. It can be detected incidentally in imaging findings or from specific symptoms encountered during follow-up.

Keywords: hyperprolactinemia, lung cancer, pituitary metastasis

Fatma Tokgoz Akyil, Emre Sedar SAYGILI, Belgit Talay, Mustafa Akyl. Pituitary Metastasis in Squamous Cell Lung Carcinoma. Respir Case Rep. 2019; 8(2): 62-66

Sorumlu Yazar: Fatma Tokgoz Akyil, Trkiye
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