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Tc-99m DTPA Klirens Ynteminin Amiodaron'un ndkledii Akcier Hasarnn Uzun Dnem Takibinde Tansal Gc [Respir Case Rep]
Respir Case Rep. 2019; 8(1): 31-34 | DOI: 10.5505/respircase.2019.59251

Tc-99m DTPA Klirens Ynteminin Amiodaron'un ndkledii Akcier Hasarnn Uzun Dnem Takibinde Tansal Gc

Zehra Pnar Ko1, Pelin zcan Kara1, Mukadder alkolu2
1Mersin Universitesi Tp Fakltesi, Nkleer Tp Anabilim Dal
2Mersin Universitesi Tp Fakltesi, Gs Hastalklar Anabilim Dal

Amiodaronun tetikledii akcier hasar (ATAH) bu ilacn doz kstlayc nemli bir yan etkisi olup tans klasik morfolojik yntemlerle zordur. Amiodaron nemli bir antiaritmik ila olsa da ciddi yan etkileri olup bunlardan birisi de akcier hasardr. Daha nceki gzlemler, Tc-99m DTPA klirensi hesaplanmasnn bu akcier hasarn gstermede doru bir yntem olduunu gstermitir. Elli sekiz yanda erkek hasta, antiaritmik ila olarak amiodaron kullanmaktayd. Hasta dispne yaknmas ile geldi ancak konvansiyonel BT sonucu tansal bir bulgu vermedi. ATAH tans ve ilacn kesilmesinden sonra uzun dnem takibinde Tc-99m DTPA grntleme yntemi kullanld. Bu olgu sunumu, Tc-99m DTPA klirensinin ATAH tans ve uzun dnem tedavi takibinde yeterli bir metod olduunu gstermektedir.

Anahtar Kelimeler: amiodaron, akcier, toksisite, DTPA, klirens.

The Diagnostic Facility of Tc-99m DTPA Clearance Method in the Long Term Follow-up of Improvement of Amiodarone-Induced Lung Damage

Zehra Pnar Ko1, Pelin zcan Kara1, Mukadder alkolu2
1Department of Nuclear Medicine, Mersin University, Mersin, Turkey
2Department of Respiratory Medicine, Mersin University, Mersin, Turkey

Amiodarone-induced lung damage (AILD) is a well-defined and important side effect of this drug which is challenging to diagnose with the classic morphological imaging methods. Although amiodarone is an efficient antiarrhythmic agent, there can be severe side effects, including lung damage. Previous observations have demonstrated that the technetium-labeled diethylenetriamine pentaacetate (Tc-99m DTPA) clearance method is an accurate imaging modality in AILD. A 58-year-old male patient who used amiodarone as an antiarrhythmic agent presented with severe dyspnea but conventional computed tomography imaging revealed nothing diagnostic. Tc-99m DTPA clearance imaging was performed for the diagnosis and long-term follow-up of AILD after cessation of treatment. This case report describes the presence of AILD and long-term follow-up results of improvement using the Tc-99m DTPA clearance method.

Keywords: amiodarone, lung, toxicity, DTPA, clearance.

Zehra Pnar Ko, Pelin zcan Kara, Mukadder alkolu. The Diagnostic Facility of Tc-99m DTPA Clearance Method in the Long Term Follow-up of Improvement of Amiodarone-Induced Lung Damage. Respir Case Rep. 2019; 8(1): 31-34

Sorumlu Yazar: Zehra Pnar Ko, Trkiye
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