Respir Case Rep. 2020; 9(1): 8-11 | DOI: 10.5505/respircase.2020.48378

Hyponatremia, Cardiac Tamponade and Carcinoembryonic Antigen in Lung Adenocarcinoma

Didar Þenocak, Tezcan Kaya, Kubilay Ýþsever, Ensar Özmen
Department of Internal Medicine, Sakarya University Faculty of Medicine, Sakarya, Turkey

Cardiac tamponade and severe hyponatremia are life-threatening and significant clinical findings. Severe hyponatremia, carcinoembryonic antigen (CEA) levels above 1000 ng/mL and cardiac tamponade are rare conditions as initial findings of non-small cell lung cancer. We report a 60-year-old man who presented with a cough, shortness of breath, nausea and loss of weight. The CEA level of the patient was 1041 ng/mL. He also had severe hyponatremia and cardiac tamponade. The patient was diagnosed with metastatic lung adenocarcinoma following an evaluation. The patient underwent chemotherapy treatment, but died 4 months after the cancer diagnosis. Severe hyponatremia, very high levels of CEA, and cardiac tamponade as initial findings of lung adenocarcinoma may be predictors of higher stage disease and poor prognosis.

Keywords: Carcinoembryonic antigen, cardiac tamponade, hyponatremia, adenocancer

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Akciðer Adenokarsinomunda Hiponatremi, Kardiyak Tamponad ve Karsinoembriyonik Antijen

Didar Þenocak, Tezcan Kaya, Kubilay Ýþsever, Ensar Özmen
Sakarya Üniversirtesi Týp Fakültesi, Ýç Hastalýklarý Anabilim Dalý, Sakarya, Türkiye

Kardiyak tamponad ve ciddi hiponatremi hayatý tehdit edebilen önemli klinik bulgulardýr. Küçük hücreli dýþý akciðer kanserinin baþlangýç bulgularýnýn ciddi hiponatremi, 1000 ng/mL’nin üzerinde karsinoembriyonik antijen (CEA) düzeyi ve kardiyak tamponad olmasý nadirdir. Bu makalede, öksürük, nefes darlýðý, bulantý ve kilo kaybý þikayetleriyle baþvuran 60 yaþýnda bir erkek hastayý sunduk. Hastanýn CEA deðeri 1041 ng/mL idi. Ayný zamanda hastada ciddi hiponatremi ve kardiyak tamponad vardý. Araþtýrma sonucu metastatik akciðer adenokarsinomu tanýsý konuldu. Hastaya kemoterapi verildi ve kanser tanýsýndan 4 ay sonra eksitus oldu. Akciðer adenokarsinomunun baþlangýç bulgularýnýn ciddi hiponatremi, çok yüksek CEA düzeyi ve kardiyak tamponad olmasý ileri evre hastalýk ve kötü prognoz göstergesi olabilir.

Anahtar Kelimeler: Karsinoembriyonik antijen, kardiyak tamponad, hiponatremi, adenokanser

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