Respir Case Rep. 2021; 10(2): 139-142 | DOI: 10.5505/respircase.2021.09821

T-Cell Acute Lymphoblastic Leukemia Presenting with Pleural Effusion: A Case Report

Hasan Furkan Avcý, Oðuzhan Okutan, Tayfun Çalýþkan, Gözde Kalbaran Kýsmet, Ýlyas Kocabað
Department of Chest Diseases, University of Health Sciences Turkey, Hamidiye Faculty of Medicine, Sultan II. Abdülhamid Han Health Application and Research Center, Ýstanbul, Turkey

Acute lymphoblastic leukemia is a heterogeneous group of lymphoid disorders that are linked to the monoclonal proliferation and expansion of immature lymphoid cells in the bone marrow, blood and organs. The clinical presentation of acute lymphoblastic leukemia is usually nonspecific, while symptoms typically include fatigue, lack of energy, easy bruising or obvious bleeding, dyspnea, dizziness and infections, and B symptoms such as fever, night sweats or weight loss can occur. Pleural effusion, as the first clinical manifestation of acute lymphoblastic leukemia, is relatively rare. We present here the case of a 55-year-old female patient diagnosed with T-cell Acute Lymphoblastic Leukemia based on examinations performed due to pleural effusion.

Keywords: Adenosine Deaminase, Leukemia, pleurisy, pleural effusion.

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Ýlk Bulgusu Plevral Effüzyon Olan T-Hücreli Akut Lenfoblastik Lösemi: Olgu Sunumu

Hasan Furkan Avcý, Oðuzhan Okutan, Tayfun Çalýþkan, Gözde Kalbaran Kýsmet, Ýlyas Kocabað
Saðlýk Bilimleri Üniversitesi, Sultan II. Abdülhamid Han Saðlýk Uygulama ve Araþtýrma Merkezi, Göðüs Hastalýklarý Servisi, Ýstanbul

Akut lenfoblastik lösemi, kemik iliði, kan ve diðer organlarda immatür lenfoid hücrelerin monoklonal proliferasyonu ve yayýlýmý ile sonuçlanan, lenfoid hastalýklar içinde heterojen bir hastalýk grubudur. Klinik prezantasyonu genelde nonspesifiktir. Bunlar içinde en sýk görülenleri, halsizlik, güç kaybý, kanamaya meyilde artýþ veya belirgin kanamalar, nefes darlýðý, baþ dönmesi ve enfeksiyonlardýr. Ateþ, gece terlemesi ve kilo kaybý gibi B semptomlarý da görülebilir. Akut lenfoblastik lösemi hastalarýnda ilk bulgu olarak plevral effüzyonun görülmesi nadir bir durumdur. Plevral effüzyon nedeniyle yapýlan tetkikler ile T-Hücreli Akut Lenfoblastik Lösemi tanýsý konan 55 yaþ kadýn hasta, burada sunulmuþtur.

Anahtar Kelimeler: Adenozin deaminaz, Lösemi, plörezi, plevral effüzyon.

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Image Slices of the Case

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