Respir Case Rep. 2014; 3(1): 11-15 | DOI: 10.5505/respircase.2014.30592

Lung involvement in Sweet's Syndrome: a rare case

Serap Argun Barýþ, Gonca Doðru, Haþim Boyacý, Ýlknur Baþyiðit, Füsun Yýldýz
Department Of Pulmonary Disease, Kocaeli University Medical Faculty, Kocaeli, Turkey

Sweet's syndrome, or acute febrile neutrophilic dermatosis, is a syndrome of erythematous papules and plaques, fever, leukocytosis, and arthralgia. Although rare, Sweet's syndrome can have extra-cutaneous manifestations, including pulmonary, cardiovascular, renal, hepatic, ocular, and neurologic. A 53-year-old man presented with a fever of 38.2 degrees Celsius associated with cough and dyspnea. There were erythematous papular lesions on the upper extremities and face. The chest X-ray and thoracic CT showed bilateral peripherally ground glass opacities. C reactive protein and erythrocyte sedimentation levels were high. There was an increase of neutrophils in bronchoalveolar lavage. The diagnosis was pulmonary involvement of Sweet's syndrome according to the clinical, radiologic and BAL findings, and the patient was treated with corticosteroid. There was a dramatic improvement of clinical, biochemical, and radiological findings 1.5 months after the treatment. Herein, the researchers report a case of Sweet's syndrome with pulmonary involvement.

Keywords: Sweet syndrome, lung, ground-glass opacity, steroid

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Nadir bir olgu: Sweet Sendromu'na baðlý akciðer tutulumu

Serap Argun Barýþ, Gonca Doðru, Haþim Boyacý, Ýlknur Baþyiðit, Füsun Yýldýz
Kocaeli Üniversitesi Týp Fakültesi Göðüs Hastalýklarý Anabilim Dalý, Kocaeli

Sweet sendromu ya da akut febril nötrofilik dermatoz, eritemli papül ve plaklar, ateþ, lökositoz ve artraljiden oluþan bir sendromdur. Nadir olarak Sweet sendromuna baðlý pulmoner, kardiyaovasküler, renal, hepatik, oküler ve nörolojik tutulumlarý içeren ekstrakutanöz tutulumlar görülebilmektedir. Elli üç yaþýnda erkek hasta nefes darlýðý, öksürük ve 38,2 derece ateþ yüksekliði þikayeti ile baþvurdu. Bir yýl önce Sweet sendromu tanýsý konulan hastanýn fizik muayenesinde her iki üst ekstremite, boyun ve yüzde eritemli papülopüstüler lezyonlar mevcuttu. PA akciðer grafisinde bilateral silik opasiteler, toraks BT’sinde her iki akciðerde periferal yerleþimli daðýnýk yamalý opasiteler izlendi. Laboratuvar tetkiklerinde, C reaktif protein ve eritrosit sedimentasyon yüksekliði izlendi. Bronkoalveoler lavaj sývýsýnda nötrofil oranýnda artýþ olan hastaya mevcut klinik ve radyolojik bulgularý ile Sweet sendromuna baðlý akciðer tutulumu tanýsý konularak steroid tedavisi baþlandý. Bir buçuk ay sonrasýnda klinik, laboratuvar ve radyolojik olarak gerileme saptandý. Sweet sendromuna baðlý pulmoner tutulum geliþen hastamýzý sunmaktayýz.

Anahtar Kelimeler: Sweet sendromu, akciðer, buzlu cam dansitesi, steroid

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