Sarcoidosis and IgA Nephropathy: a Rare Association

Sarcoidosis a systemic chronic granulomatous disease characterized by noncaseating granulomas in the involvement organs. The etiology of the disease has yet to be precisely defined. The prevalence of sarcoidosis is 0.1-640 per one hundred thousand. In addition to the lungs, the other commonly involved organs are the skin, eyes, and joints. In previous investigations renal disorders were reported as 0.9% of sarcoidosis cases. In 50% of these cases, calcium metabolism disorders were found. However, proteinuria and hematuria are not common complications of sarcoidosis. This case report aims to argue for the rare association of sarcoidosis and IgA nephropathy, by presenting a case with proteinuria and IgA nephropathy in the renal biopsy.

Sarkoidoz ve IgA Nefropatisi (Nadir Bir Birliktelik)

arkoidoz, yüz binde 0,1-640 prevalansý olan, sebebi net olarak bilinmeyen, tutulan organlarda nonkazeifiye granülomlarla kendini gösteren, sistemik kronik granülomatöz bir hastalýktýr. Akciðer dýþýnda cilt, göz, eklem tutulumlarý belirgindir. Böbrek tutulumunun %0,9 oranýnda olduðunu gösteren çalýþmalar mevcuttur. Olgularýn %50’sinde kalsiyum metabolizmasý bozukluðu bulunmaktadýr. Ancak proteinüri, hematüri gibi bulgular sarkoidozda beklenen komplikasyonlar arasýnda deðildir. Takipleri sýrasýnda belirgin proteinüri görülen ve yapýlan böbrek biyopsisinde IgA nefropatisi saptanan sarkoidoz tanýlý hastayý literatürler eþliðinde tartýþtýk.