A Case of Granular Cell Tumor of the Mediastinum Treated by VATS and A Review of Literature

Demir�z, �evki Mustafa; F�nd�k, G�kt�rk; Y�lmaz, G�l�en; Demirag, Funda; Tar�, P�nar

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A Case of Granular Cell Tumor of the Mediastinum Treated by VATS and A Review of Literature [Respir Case Rep]

Respir Case Rep. 2020; 9(1): 20-24 | DOI: 10.5505/respircase.2020.47123

A Case of Granular Cell Tumor of the Mediastinum Treated by VATS and A Review of Literature

�evki Mustafa Demir�z¹, G�kt�rk F�nd�k¹, G�l�en Y�lmaz¹, Funda Demirag², P�nar Tar�³
¹University Of Health Scienes, Ankara Atat�rk Chest Diseases And Thoracic Surgery Training And Research Hospital, Department of Thoracic Surgery,Ankara, Turkey
²University Of Health Scienes, Ankara Atat�rk Chest Diseases And Thoracic Surgery Training And Research Hospital, Department of Pathology,Ankara, Turkey
³University Of Health Scienes, Ankara Atat�rk Chest Diseases And Thoracic Surgery Training And Research Hospital, Department of Nuclear Medicine,Ankara, Turkey

Granular cell tumors (GCT) of mediastinal origin are extremely rare. To the best of our knowledge there have been a total of 21 cases reported since the first case was reported by Harrer in 1972. Both benign and malign forms of GCTs have been reported, and some criteria for malign forms have been described. Preoperative diagnoses are challenging due to the rareness of the condition. Histopathological studies should include immunhistochemistry. Given the rareness of such tumors in the mediastinum, the findings and the diagnostic yield of PET-CT are still unclear. Herein we present the case of a 50-year-old woman suffering from back pain whose diagnosis was based on a thorax computed tomography followed by PET-CT, and who was treated with a video-assisted thoracic surgical excision, with a final pathologic diagnosis of a �granular cell tumor� of the posterior mediastinum.

Keywords: granular cell tumor, mediastinal tumor, video-assisted thoracic surgery

VATS ile Tedavi Edilen Mediastinal Gran�ler H�creli T�m�r Olgusu ve Literat�r �ncelemesi

�evki Mustafa Demir�z¹, G�kt�rk F�nd�k¹, G�l�en Y�lmaz¹, Funda Demirag², P�nar Tar�³
¹Sa�l�k Bilimleri �niversitesi, Ankara Atat�rk G��s Hastal�klar� Ve G��s Cerrahisi SUAM, G��s Cerrahisi Klini�i, Ankara
²Sa�l�k Bilimleri �niversitesi, Ankara Atat�rk G��s Hastal�klar� Ve G��s Cerrahisi SUAM, Patoloji Klini�i, Ankara
³Sa�l�k Bilimleri �niversitesi, Ankara Atat�rk G��s Hastal�klar� Ve G��s Cerrahisi SUAM, N�kleer T�p Klini�i, Ankara

Mediastinal Gran�ler H�creli T�m�r (GHT) olduk�a nadirdir. �lk kez 1972 y�l�nda Harrer taraf�ndan bildirildi�i tarihten beri literat�rdeki toplam olgu say�s� 21�dir. GHT�nin hem benign hem de malign formlar� bildirilmi�, malignite kriterleri de tan�mlanm��t�r. Olduk�a nadir bir t�m�r olmas� nedeniyle ay�r�c� tan�da d��n�lmedi�inden preoperatif tan�s� zordur. Histopatolojik incelemeler mutlaka imm�nhistokimyasal �al��malar� da i�ermelidir. Mediastende nadir g�r�len bir t�m�r� oldu�undan, tan�da PET/BT�nin etkinli�i de hen�z belirlenmemi�tir. Sunulan olguda, s�rt a�r�s� ile ba�vuran 50 ya��nda bir kad�n hastaya, toraks tomografisi ve takiben PET/BT �ekilmi�, posterior mediastinal b�lgede saptanan lezyona y�nelik VATS ile total eksizyon yap�lm��t�r. Histopatolojik tan� �gran�ler h�creli t�m�r� olarak raporlanm��t�r.

Anahtar Kelimeler: Gran�ler H�creli T�m�r, Mediastinal T�m�r, Video-yard�ml� G��s Cerrahisi

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Corresponding Author: �evki Mustafa Demir�z, T�rkiye
Manuscript Language: English

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