Respir Case Rep. 2016; 5(3): 157-160 | DOI: 10.5505/respircase.2016.53765

Penile Sarcoidosis: A Rare Initial Manifestation

Sibel Doruk¹, Eyüp Sabri Uçan², Faruk Doðan³, Funda Taþlý⁴, Hasan Umut Kantarcý⁵, Gülistan Karadeniz¹, Kemal Can Tertemiz^2
1Sifa University Department Of Pulmonary Medicine, Izmi̇r
²Dokuz Eylul University Department Of Pulmonary Medicine, Izmi̇r
³Sifa University Department Of Urology, Izmi̇r
⁴Sifa University Department of Pathology, Izmir
⁵Sifa University Department of Radiology, Izmir

Sarcoidosis is a multi-systemic disease and genitourinary involvement is rarely seen. Penile involvement is even rarer among genitourinary sarcoidosis. In this article, we present two cases of penile sarcoidosis. The first case was admitted to our urology clinic with penile itching and pain and his symptoms did not improve with non-specific antibiotic therapy. In biopsy, non-caseified granulomatous inflammation was detected. He did not have any systemic and pulmonary compliant. The second case was admitted to our urology clinic with penile nodules and nodules were excised for diagnosis. In dermis biopsy, multiple multi-nuclear giant cells and granulomas were detected. He had shortness of breath, wheezing, and sweating. He was treated with systemic prednisolone. Both cases were successfully treated with pharmacological treatments.

Keywords: sarcoidosis, genitourinary sarcoidosis, penile sarcoidosis

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Penil Sarkoidoz: Nadir ilk tutulum

Sibel Doruk¹, Eyüp Sabri Uçan², Faruk Doðan³, Funda Taþlý⁴, Hasan Umut Kantarcý⁵, Gülistan Karadeniz¹, Kemal Can Tertemiz^2
1Þifa Üniversitesi Göðüs Hastalýklarý Ad., Ýzmi̇r
²Dokuz Eylül Üniversitesi Göðüs Hastalýklarý Ad., Ýzmi̇r
³Þifa Üniversitesi Üroloji Ad., Ýzmi̇r
⁴Þifa Üniversitesi Patoloji Ad., Ýzmi̇r
⁵Þifa Üniversitesi Radyoloji Ad., Ýzmi̇r

Sarkoidozis genitoüriner sistemin nadiren tutulduðu sistemik bir hastalýktýr ve penis tutulumu ise genitoüriner sarkoidoz olgularý arasýnda çok daha nadir görülür. Bu makalede penis sarkoidozu tanýsý konulan ve takip edilen iki olgu literatür eþiliðinde sunulmuþtur. Ýlk olgu üroloji kliniðine peniste kaþýntý ve aðrý yakýnmasý ile baþvurmuþtu ve bu yakýnmalarý nonspesifik antibiyotik tedavi ile gerilememiþti. Biyopside nonkazifiye granülomatöz inflamasyon izlendi. Herhangi bir sistemik ve solunumsal yakýnmasý yoktu. Lokal kortikosteroid tedavi verildi. Ýkinci olgu da üroloji kliniðine peniste nodül yakýnmasý ile baþvurmuþtu ve nodül eksize edilmiþti. Biyopsi örneðinde dermisde multinukleer dev hücreler ve granülomlar izlendi. Nefes darlýðý, hýrýltý ve terleme yakýnmasý olan hastaya sistemik prednizolon tedavisi baþlandý. Ýki olgunun da yakýnmalarý uygulanan bu tedaviler ile düzeldi.

Anahtar Kelimeler: sarkoidoz, genitouriner sarkoidoz, penis sarkoidozu

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