Respir Case Rep. 2021; 10(1): 12-15 | DOI: 10.5505/respircase.2021.78055

Bleomycin-Induced Fatal Lung Toxicity Misdiagnosed as Covid-19 Pneumonia: A Case Report

Murathan Köksal¹, Yasin Celal Güneþ^2
1Ministry of Health Ankara City Hospital
²SBU Ankara Kecioren SUAM

Bleomycin is a chemotherapeutic agent that is preferred for the treatment of testicular cancer, lymphoma and some squamous cell carcinomas. Bleomycin-induced lung toxicity is a common, but rarely fatal side-effect, and the radiological image of which can be confused with other reasons which makes organizing pneumonia pattern. We report here on the case of a 40-year-old male patient with testicular cancer with bleomycin-induced fatal lung toxicity that was misdiagnosed as Covid-19 pneumonia. The patient suffered subsequent fatal spontaneous pneumomediastinum, pneumothorax, and pulmonary interstitial and subcutaneous emphysema, and died from respiratory failure.

Keywords: bleomycin, lung toxicity, covid-19, organizing pneumonia

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Covid 19 Pnömonisi ile Karýþan Bleomisine Baðlý Fatal Akciðer Toksisitesi: Olgu Sunumu

Murathan Köksal¹, Yasin Celal Güneþ^2
1Saðlýk Bakanlýðý Ankara Þehir Hastanesi
²SBÜ Ankara Keçiören SUAM

Bleomisin testis kanseri, lenfoma ve bazý skuamöz hücreli kanserlerin tedavisinde tercih edilen kemoterapotik bir ajandýr. Bleomisine baðlý akciðer toksisitesi sýk karþýlaþýlmakla birlikte nadiren fatal yan etkiye neden olmaktadýr. Ayrýca bleomisine baðlý akciðer hasarýnýn radyolojik görüntüleri diðer organize pnömoni paterni yapan nedenler karýþabilmektedir. Bu olgu sunumunda bilinen testis kanseri tanýsý olan 40 yaþýnda erkek hastanýn, Covid 19 pnömonisi ile karýþan bleomisin baðlý fatal akciðer hasarý sunulmaktadýr. Hasta bu zeminde spontan fatal pnömotoraks, pnömomediasten ve pulmoner intersisyal ve subkütan amfizem geliþimi nedeniyle respiratuar arrest kaynaklý kaybedilmiþtir..

Anahtar Kelimeler: bleomisin, akciðer toksisitesi, covid-19, organize pnömoni

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Image Slices of the Case

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