Respir Case Rep. 2021; 10(2): 130-134 | DOI: 10.5505/respircase.2021.94899

Swyer-James-Macleod Syndrome and Antiphospholipid Antibody Syndrome: A Rare Case Report

Melike Yüksel Yavuz¹, Ahmet Daylan^2
1Department of Chest Diseases, Ýzmir Çiðli Training and Research Hospital, Ýzmir, Turkey
²Department of Cardiovascular Surgery, Ýzmir Çiðli Training and Research Hospital, Ýzmir, Turkey

Swyer-James-Macleod syndrome (SJMS) is an entity of obliterative bronchiolitis, the etiology of which has been linked to childhood infections of the lower respiratory tract. Patients may not be diagnosed until older ages, and is based on noninvasive thoracic imaging methods and under the guidance of the patients' history. Antiphospholipid antibody syndrome (AFAS) is a multisystemic autoimmune disease that manifests with recurrent vascular thrombosis, unexplained fetal losses and thrombocytopenia, with 70% of cases being female. It should also be kept in mind in the differential diagnosis of recurrent or unusual thrombosis and unprovoked thrombosis at young ages. A 33-year-old male patient who presented with acute peripheral thrombus underwent a pulmonologist consultation due to dyspnea, and was diagnosed with SJMS. After further investigations during follow-up, the patient was diagnosed with AFAS. We report on this case due to the synchronous coexistence of these two rare syndromes.

Keywords: Swyer-James-Macleod Syndrome, Antiphospholipid antibody syndrome, deep vein thrombosis.

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Swyer-James-Macleod Sendromu ve Antifosfolipid Antikor Sendromu: Nadir Bir Olgu Sunumu

Melike Yüksel Yavuz¹, Ahmet Daylan^2
1Ýzmir Çiðli Eðitim ve Araþtýrma Hastanesi, Göðüs Hastalýklarý Bölümü, Ýzmir
²Ýzmir Çiðli Eðitim ve Araþtýrma Hastanesi, Kalp ve Damar Cerrahisi Bölümü, Ýzmir

Swyer-James-Macleod sendromu (SJMS), etiyolojisinde çocukluk çaðý alt solunum yolu enfeskiyonlarýnýn yer aldýðý düþünülen obliteratif bronþiolitis durumudur. Hastalar ileri yaþlara kadar taný alamayabilir. Noninvaziv toraks görüntüleme yöntemleri ve öykü ile tanýsý konulmaktadýr. Antifosfolipid antikor sendromu (AFAS) tekrarlayan vasküler tromboz, nedeni açýklanamayan fetal kayýplar ve trombositopeni ile seyreden multisistemik otoimmün bir hastalýktýr. Hastalarýn yüzde 70’i kadýndýr. Erkek hastalar için de tekrarlayan veya olaðan dýþý trombozlarda ve genç yaþtaki unprovake trombozu olan olgularda ayýrýcý tanýda akýlda tutulmalýdýr. Akut periferik trombüs klinik tablosunda baþvuran 33 yaþýndaki erkek olgu dispne nedeniyle göðüs hastalýklarýna konsülte edildi ve SJMS tanýsý aldý. Takiplerde, yapýlan ileri tetkikler sonrasýnda, hastaya AFAS tanýsý konuldu. Olgumuz, nadir görülen bu iki sendromun eþ zamanlý birlikteliði nedeniyle bildirilmiþtir.

Anahtar Kelimeler: Swyer-James-Macleod Sendromu, Antifosfolipid Antikor Sendromu, derin ven trombozu

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