Respir Case Rep. 2018; 7(2): 123-126 | DOI: 10.5505/respircase.2018.97659

Radiographic and scintigraphic correlation in a patient with pulmonary alveolar microlithiasis

Arzu Cengiz¹, Emel Ceylan², Can Zafer Karaman^3
1Adnan Menderes University Faculty Of Medicine, Department Of Nuclear Medicine, Aydýn, Turkey
²Adnan Menderes University, Faculty Of Medicine, Department Of Chest Disease, Aydýn, Turkey
³Adnan Menderes University, Faculty Of Medicine, Department Of Radiology, Aydýn, Turkey

Pulmonary alveolar microlithiasis (PAM) is a rare, idiopathic lung disease that leads to alveolar deposition of calcium phosphate microliths. Most patients are asymptomatic, but radiological features are quite marked and are nearly pathognomonic. Bone scintigraphy can be useful in the detection of early pulmonary calcifications. The imaging findings of a 65-year-old male patient who was diagnosed with PAM are described in this report. He presented with nonspecific chest pain, shortness of breath, wheezing, and a cough ongoing for 4 years. There was fine reticular and nodular infiltration seen on a chest X-ray. Chest computed tomography images revealed bilateral, diffuse, fine, calcified interstitial nodules and nodular septal thickening in the middle and lower lung zones. A whole body bone scintigraphy with technetium-99m methylene diphosphonate (Tc-99m MDP) revealed bilateral, diffuse uptake in the pulmonary parenchyma.

Keywords: Pulmonary alveolar microlithiasis, X-Ray computed tomography, bone scintigraphy

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Pulmoner alveoler mikrolitiyazisli bir hastada radyografik ve sintigrafik korelasyon

Arzu Cengiz¹, Emel Ceylan², Can Zafer Karaman^3
1Adnan Menderes Üniversitesi Týp Fakültesi, Nükleer Týp Anabilim Dalý, Aydýn
²Adnan Menderes Üniversitesi Týp Fakültesi, Göðüs Hastalýklarý Anabilim Dalý, Aydýn
³Adnan Menderes Üniversitesi Týp Fakültesi, Radyoloji Anabilim Dalý, Aydýn

Pulmoner alveolar mikrolitiyazis (PAM), alveoler kalsiyum fosfat mikrolitlerinin birikimine yol açan, nedeni bilinmeyen nadir bir hastalýktýr. Hastalarýn çoðu asemptomatiktir, fakat radyolojik özellikleri oldukça gürültülü ve neredeyse patognomoniktir. Kemik sintigrafisi erken pulmoner kalsifikasyonlarýn saptanmasýnda kullanýlabilir. Bu yazýda, PAM tanýsý alan 65 yaþýnda bir erkek hastanýn görüntüleme bulgularý sunulmuþtur. Hasta, dört yýldýr devam eden nonspesifik göðüs aðrýsý, nefes darlýðý, hýrýltý ve öksürük þikayetleriyle baþvurdu. Akciðer grafisinde ince retiküler ve nodüler infiltrasyon vardý. Toraks bilgisayarlý tomografisi, bilateral orta ve alt zonlarda ince kalsifiye intersitisyel nodüller ve septal kalýnlaþma gösterdi. Teknesyum 99m metilen difosfonat (Tc-99m MDP) ile yapýlan tüm vücut kemik sintigrafisinde pulmoner parankimde bilateral diffüz tutulum izlendi.

Anahtar Kelimeler: Pulmoner alveoler mikrolitiyazis, X-Ray bilgisayarlý tomografi, kemik sintigrafisi

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