Respir Case Rep. 2019; 8(2): 40-43 | DOI: 10.5505/respircase.2019.03779

Sistemik Lupus Eritematozusta Ýnterstisyel Akciðer Hastalýðý

Gina Amanda, Prima Belia Fathana, Dianiati Kusumo Sutoyo
Endonezya Üniversitesi Týp Fakültesi, Persahabatan Has-tanesi, Pulmonoloji ve solunum Týbbi AD, Endonezya

Nedeni bilinen interstisiyel akciðer hastalýklarýnýn (ÝAH) etyolojilerinden birisi de bað dokusu hastalýklarý (BDH)'dýr. Nedeni bilinen ÝAH’ya yol açana BDH arasýnda, sistemik skleroz, romatoid artrit, miks bað dokusu hastalýklarý ve Sjögren sendromu sýklýkla bulunmaktadýr. Ancak sistemik lupus eritematozus (SLE) hastalarýnda bu durum nadiren görülür. SLE’de ÝAH tanýsý koymak zordur. Hava yolu hastalýklarý, pulmoner infeksiyon ve vasküler anormallikler gibi diðer pulmoner tutulumlar öncelikle ekarte edilmelidir. SLE de ve diðer BDH olan ÝAH hastalarýnýn tedavisinde kortikosteroidler ve diðer immünsüpressif ilaçlar kullanýlýr. Burada ÝAH olan iki SLE olgusu sunulmaktadýr. Bir olguda SLE’nin ilk bulgusu ÝAH idi, diðer olguda SLE tanýsýndan sonra ÝAH görüldü.

Anahtar Kelimeler: konnektif doku hastalýklarý, interstisyel akciðer hastalýðý, sistemik lupus eritematozus

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Interstitial Lung Disease in Systemic Lupus Erythematosus

Gina Amanda, Prima Belia Fathana, Dianiati Kusumo Sutoyo
Department of Pulmonology and Respiratory Medicine, Faculty of Medicine Universitas Indonesia, Persahabatan Hospital, Jakarta, Indonesia

Connective tissue disease (CTD) is one of the etiologies of known-cause interstitial lung disease (ILD) that is frequently found with systemic sclerosis, rheumatoid arthritis, mixed-CTD and Sjӧgren syndrome, but which occurs rarely in systemic lupus erythematosus (SLE) patients. A diagnosis of ILD in SLE can be challenging, as the physician should first exclude other pulmonary involvements, including airway disorders, pulmonary infection and vascular abnormality. The management of ILD in SLE and other CTDs patients includes corticosteroid and other immunosuppressive medications. Here we report on two ILD in SLE cases: in one case, ILD was the first sign of SLE; and in the other, ILD appeared after the diagnosis of SLE had been established.

Keywords: connective tissue disease, interstitial lung disease, systemic lupus erythematosus

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ATIF KOPYALA