Primer Plevral Sinovyal Sarkom Olgusu

Cano�lu, Kadir; Y�lmaz, �smail; Cal��kan, Tayfun; Ayten, �mer; Okutan, O�uzhan; Kartalo�lu, Zafer; Kaya Terzi, Neslihan

Cilt : 11 Say� : 2 Y�l : 2024

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Primer Plevral Sinovyal Sarkom Olgusu [Respir Case Rep]

Respir Case Rep. 2022; 11(2): 88-92 | DOI: 10.5505/respircase.2022.85579

Primer Plevral Sinovyal Sarkom Olgusu

Kadir Cano�lu¹, �smail Y�lmaz², Tayfun Cal��kan¹, �mer Ayten¹, O�uzhan Okutan¹, Zafer Kartalo�lu¹, Neslihan Kaya Terzi³
¹Sa�l�k Bilimleri �niversitesi, Sultan 2. Abd�lhamid Han E�itim ve Ara�t�rma Hastanesi, G��s Hastal�klar� Klini�i, �stanbul
²Sa�l�k Bilimleri �niversitesi, Sultan 2. Abd�lhamid Han E�itim ve Ara�t�rma Hastanesi, Patoloji Klini�i, �stanbul
³Sa�l�k Bilimleri �niversitesi, Gaziosmanpa�a E�itim ve Ara�t�rma Hastanesi, Patoloji Klini�i, �stanbul

Primer plevral sinovyal sarkom tan�l� 29 ya��nda erkek hastan�n, geli�inde herhangi bir �ikayeti yoktu, sigara i�miyordu ve �zge�mi�inde �zellik yoktu. PA akci�er grafisinde, g��s duvar�na biti�ik d�zg�n s�n�rl� dev kitle izlendi. Toraks BT�sinde; sa� hemitoraks latera-linde, diff�z amorf kalsifikasyon i�eren solid kitlesel lezyon tespit edildi. PET/BT�de, tan�mlanan lezyonda SUVmax 5.0 olan F18-FDG tutulumu saptand�. Tru-cut biyopsi sonucunda, histolojik olarak monofazik, yo�un h�cresel ve birbiri �zerine ge�en fasik�llerin olu�turdu�u i�si h�creler, SYT-SSX1 f�zyon (X;18)(p11.23;q11) saptanmas� �zerine sinovyal sarkom tan�s� kondu. Cerrahi ve kemoradyoterapi sonras�nda 1 y�ld�r stabil olarak onkoloji merkezinde takip edilmektedir. Bu yaz�, nadir g�r�len ve agresif bir tumor olan primer plevral sinovyal sarkomun tan� basamaklar� ve iyi sonu�lar al�nabilmesi i�in h�zl�ca tedavisinin ba�lanmas�na dikkat �ekmeyi ama�lamak-tad�r.

Anahtar Kelimeler: Akci�er kanseri, plevra, sinovyal sarkom

A Case of Primary Pleural Synovial Sarcoma

Kadir Cano�lu¹, �smail Y�lmaz², Tayfun Cal��kan¹, �mer Ayten¹, O�uzhan Okutan¹, Zafer Kartalo�lu¹, Neslihan Kaya Terzi³
¹Department of Pulmonology, Health Science University, Sultan II. Abd�lhamid Han Training and Research Hospital, �stanbul, T�rkiye
²Department of Pathology, Health Science University, Sultan II. Abd�lhamid Han Training and Research Hospital, �stanbul, T�rkiye
³Department of Pathology, Health Science University, Gaziosmanpa�a Training and Research Hospital, �stanbul, T�rkiye

We present here the case of a 29-year-old male with primary pleural synovial sarcoma. The patient had no complaints, no significant medical history and did not smoke. A well-circumscribed giant mass, adjacent to the chest wall was observed on a PA chest X-ray, with a solid mass lesion in the lateral right hemithorax with diffuse amorphous calcifications noted on thorax computed tomography. An F18-FDG uptake with a SUVmax of 5.0 was detected in the mass defined by PET/CT. A Tru-cut biopsy revealed monophasic as histological subtypes composed of a dense cellular and interlaced fascicular proliferation of spindle cells, and SYT-SSX1 fusion (X;18)(p11.23;q11) consistent with synovial sarcoma. The patient was followed-up in the oncology center after surgery and chemoradio-therapy, and has been stable for 1 year. This paper draws attention to a diagnostic approach to primary pleural synovial sarcoma, which is a rare and aggres-sive tumor, and the need for the prompt initiation of treatment for an improved outcome.

Keywords: Lung cancer, pleura, synovial sarcoma

Sorumlu Yazar: Kadir Cano�lu, T�rkiye
Makale Dili: �ngilizce

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