Respir Case Rep. 2019; 8(2): 58-61 | DOI: 10.5505/respircase.2019.23600

Bir Kadýn Hastada Corynebacterium striatum baðlý Trakeal Enfeksiyon: Olgu Sunumu

Panagiota Xaplanteri¹, Efstratios N. Koletsis², Christos Prokakis², Iris Spiliopoulou¹, Dimitrios Dougenis³, Fevronia Kolonitsiou^1
1Patrasya Üniversitesi Genel Hastanesi, Mikrobiyoloji Anabilim Dalý, Yunanistan
²Patrasya Üniversitesi Genel Hastanesi Kalp ve Damar Cerrahisi Anabilim Dalý, Yunanistan
³Atina Kalp Cerrahisi Bölümü Attikon Üniversitesi Hastanesi, Yunanistan

Nondifteriyal Corynebacteria insan cildi ve mukozalarýnda sýklýkla normal flora olarak kolonize olur. Ýmmün yetmezliði ya da kritik hastalýðý olanlarda fýrsatçý patojenler olarak ortaya çýkar. Corynebacterium striatum insanda, nadiren patojen olarak bildirilmiþtir. Bu yazýda, daha önce hastahanenin Acil Servis'ine giderek artan dispne ve inspiratuvar wheezing bulgularýyla baþvuran ve Yoðun Bakým Servisinde yatýrýlarak tedavi gören 62 yaþýnda beyaz kadýn hasta sunulmuþtur. Muayene, laboratuar ve görüntüleme bulgularý, guatr’a baðlý eski trakeostomi sonrasý geliþen enfeksiyonun neden olduðu Trakeal Stenoz ile uyumluydu. Kültürde çoklu antibiyotiklere dirençli C. striatum izole edildi. Hasta subtotal tiroidektomi, trakeal rezeksiyon ve tigecycline ile tedavi edildi. Ameliyat sonrasý iyileþme, travmatik enfeksiyonun açýk drenaj ve antibiyotiklerle tedavi edilmesi nedeniyle komplike oldu. Uzun süren iyileþme döneminde baþkaca komplikasyonlar olmaksýzýn taburcu edildi.

Anahtar Kelimeler: Corynebacterium striatum, multiple-ilaç direnci, fýrsatçý enfeksiyonlar, tigecycline

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Tracheal Infection due to Corynebacterium striatum in a Female Patient: A Case Report

Panagiota Xaplanteri¹, Efstratios N. Koletsis², Christos Prokakis², Iris Spiliopoulou¹, Dimitrios Dougenis³, Fevronia Kolonitsiou^1
1Department of Microbiology, University General Hospital of Patras, Greece
²Department of Cardiothoracic Surgery, University General Hospital of Patras, Greece
³Department of Cardiac Surgery, Attikon University Hospital of Athens, Greece

Nondiphtherial corynebacteria commonly colonize as normal flora on human skin and mucous membranes, and represent an emerging opportunistic pathogen for immunocompromised or critically ill patients. Corynebacterium striatum has seldom been reported as a human pathogen. Here we present the case of a 62-year-old Caucasian female patient who was previously hospitalized in the Intensive Care Unit, and who attended the emergency department with worsening dyspnea and inspiratory wheezing. The findings of a thorough examination, laboratory tests and imaging were consistent with tracheal stenosis, inflammation related to a previous tracheostomy and a submerged thyroid goiter. A multi-drug resistant C. striatum stain was isolated. The patient was treated with a subtotal thyroidectomy, tracheal resection and tigecycline. Postoperative recovery was complicated by a trauma infection treated with open drainage and antibiotics, and after a long recovery period, the patient was discharged home without further complications.

Keywords: Corynebacterium striatum, multi-drug resistance, opportunistic infections, tigecycline

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ATIF KOPYALA