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Plevral Tutulum ile Seyreden Sarkoidoz [Respir Case Rep]
Respir Case Rep. 2014; 3(1): 16-19 | DOI: 10.5505/respircase.2014.26349

Plevral Tutulum ile Seyreden Sarkoidoz

Hatice Kutbay zelik1, Mehmet Bayram1, Nur Pnar Bykbal2, Abdullah Kansu1, Muhammed Emin Akkoyunlu1, Murat Sezer1, Fatmanur Karakse1, Fatih Yakar1, Levent Kart1
1Bezmialem Vakf niversitesi Gs Hastalklar Anabilim Dal
2Bezmialem Vakf niversitesi Patoloji Anabilim Dal

Sarkoidoz, nedeni bilinmeyen, en sk akcierleri ve intratorasik lenf nodlarn tutan, multisistemik, nonkazeifiye granlomatz bir hastalktr. Literatrde plevra svs grlme skl %0-5 arasnda bildirilmektedir. Tan plevra biyopsisinde kazeifikasyon nekrozu iermeyen granlom gsterilmesi ve granlom yapan dier nedenlerin dlanmas ile konulur. Kuru ksrk ve sol yan ars ikayeti ile poliklinie bavuran 26 yanda erkek hastann fizik muayenesinde sol hemitoraksta solunum seslerinde azalma dnda dier sistem muayenelerinde zellik yoktu. Akcier grafisinde; bilateral hiler genileme, solda plevral efzyon ve sol st zonda nonhomojen dansite art tespit edildi. Bronkoskopiyi tolere edemeyen hastaya video yardml torakoskopi (VATS ) uyguland. Plevra ve mediastinal lenf bezi rnekleri histopatolojisi nekrozlamayan granlomatz iltihap, sarkoidoz ile uyumlu olarak raporland. Metilprednisolon (0.5 mg /kg /gn) balanan hastann akcier grafisindeki lezyonlarda regresyon tespit edildi. Plrezi tespit ettiimiz hastalarda, tberkloz insidansi yksek olan yerlerde bile sarkoidozun akla gelmesi asndan bu olguyu sunmay uygun bulduk.

Anahtar Kelimeler: sarkoidoz, plevral efzyon, video yardml torakoskopi

Sarcoidosis Presenting with Pleural Involvement

Hatice Kutbay zelik1, Mehmet Bayram1, Nur Pnar Bykbal2, Abdullah Kansu1, Muhammed Emin Akkoyunlu1, Murat Sezer1, Fatmanur Karakse1, Fatih Yakar1, Levent Kart1
1Bezmialem Vakf University Department Of Chest Deseases
2Bezmialem Vakf University Department Of Patology

Sarcoidosis is a multisystemic, granulomatous disease with particular involvement in the lungs and intrathoracic lymph nodes. The prevalence of pleural fluid occurs in 0-5% of the cases in the literature. Diagnosis depends on non-caseating granulomas in the biopsy and the exclusion of other possible reasons. A 26-year-old male admitted with cough and left sided chest pain. Physical examination was normal except a decrease in respiratory sounds in the left hemithorax. The chest x-ray showed bilateral hilar enlargement, pleural fluid in the left hemithorax, and non-homogenous density in the left upper zone. Video-assisted thoracosopic surgery (VATS) was performed because the patient could not tolerate bronchoscopy. The histopathological examination of samples reported non-necrotizing granulomatous inflammation. Methylprednisolone (0.5 mg/kg/day) was initiated. Regression of lymphadenopathies, pleural effusion, and parenchymal opacities were present at the fifth month of therapy. This case emphasizes the possibility of sarcoidosis in patients with pleural effusion, even in places where tuberculosis prevalence is high.

Keywords: sarcoidosis, pleural effusion, video-assisted thoracoscopy

Hatice Kutbay zelik, Mehmet Bayram, Nur Pnar Bykbal, Abdullah Kansu, Muhammed Emin Akkoyunlu, Murat Sezer, Fatmanur Karakse, Fatih Yakar, Levent Kart. Sarcoidosis Presenting with Pleural Involvement. Respir Case Rep. 2014; 3(1): 16-19

Sorumlu Yazar: Hatice Kutbay zelik, Trkiye
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