e-ISSN 2147-2475
Cilt : 11 Say : 3 Yl : 2022

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Tm ilk seenek antitberkloz ilalarna kar fiks ila dknts gelien akcier tberklozu [Respir Case Rep]
Respir Case Rep. 2017; 6(2): 82-85 | DOI: 10.5505/respircase.2017.51423

Tm ilk seenek antitberkloz ilalarna kar fiks ila dknts gelien akcier tberklozu

Gina Amanda, Fariz Nurwidya, Fathiyah Isbaniyah
Endonezya niversitesi, Gs Hastalklar Servisi, Jakarta, Endonezya

Tberkloz tm Dnyada nemli bir mortalite nedeni olmaya devam etmektedir. Antitberkloz tedavi srasnda kullanlan ilalarla, allerjik veya non-allerjik reaksiyonlar eklinde yan etkiler ortaya kmaktadr. Ciddi reaksiyonlar nadir grlmekle beraber, ilaca bal cilt reaksiyonlar antitberkloz ilalarn en sk grlen yan etkileridir. Burada, ilk seenek antitberkloz ilalarn tmne kar fiks ila dknts olan akcier tberklozlu 34 yandaki erkek olguyu sunuyoruz. Antitberkloz ilalarn almndan sonra hastann tm vcudunda ok sayda erozyon ve kabarcklar olutu. Cilt biyopsisi yapld ve sonucu epidermal ve sub-epidermal bller olarak tanmland. Hastann durumu ar hiposemi nedeniyle ktlemeye balad. Ne yazk ki, fiks ila dknts tedavisi srasnda hasta vefat etti.

Anahtar Kelimeler: ila yan etki, antitberkloz ila, ila dknts, tberkloz

Pulmonary tuberculosis with fixed drug eruption to all first-line anti-tuberculosis drugs

Gina Amanda, Fariz Nurwidya, Fathiyah Isbaniyah
Department Of Pulmonology And Respiratory Medicine, Universitas Indonesia, Jakarta, Indonesia

Tuberculosis (TB) is still one of the leading causes of mortality worldwide. Treatment with anti-TB drugs sometimes results in side effects for patients, including drug reactions, both allergic and non-allergic. Cutaneous adverse drug reaction is the most common side effect of anti-TB drugs, but severe reaction is rare. Here, we report rare case of a 34-year-old male who presented with pulmonary TB and fixed drug eruption to all first-line anti-TB therapies. After ingesting anti-TB regimen, multiple skin erosions and blisters occurred. Skin biopsy was performed and result was epidermis with subepidermal bullous. The patients condition deteriorated, he developed severe hypoxemia, and unfortunately, he died during fixed drug eruption treatment.

Keywords: adverse drug reaction, anti-tuberculosis drugs, drug eruption, tuberculosis

Gina Amanda, Fariz Nurwidya, Fathiyah Isbaniyah. Pulmonary tuberculosis with fixed drug eruption to all first-line anti-tuberculosis drugs. Respir Case Rep. 2017; 6(2): 82-85

Sorumlu Yazar: Gina Amanda, Indonesia
Makale Dili: ngilizce
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