Tedaviye Dramatik Yanýt Veren Akut Ýdyopatik Nonspesifik Pnömoni Olgusu

Nonspesifik interstisyel pnömoni (NSÝP), idiopatik interstisiyel pnömonilerin bir formudur. Spesifik histolojik paternini, deðiþken derecelerde alveolar duvar inflamasyonu veya fibrozis eþlik eden temporal uniform lezyonlar oluþturur. Organize komponent deðiþik derecelerde bulunabilir ve histolojik olarak organize komponentin varlýðý NSÝP tanýsýný dýþlatmaz. Akut solunum yetmezliði NSÝP'te nadir görülür. Radyolojik olarak yaygýn konsolidasyon bulgularý ve akut solunum yetmezliði tablosunda kliniðimize baþvuran kadýn hastaya, cerrahi akciðer biyopsisi yapýlmýþ ve organize pnömoni komponentli NSÝP tanýsý konmuþtur. Steroid tedavisine hýzlý cevap gözlenmiþ ve klinik bulgular dramatik olarak düzelmiþtir. Organize pnömoni komponentili idiopatik NSÝP olgularýnýn solunum yetmezliði ile baþvurabileceklerini ve hýzlý taný ve tedavinin bu hastalardaki önemini vurgulamak amacýyla olgumuzu sunuyoruz.

A Case of Acute Idiopathic Non-specific Pneumonia with Dramatic Response to Treatment

Non-specific interstitial pneumonia (NSIP) is a form of idiopathic interstitial pneumonia with a specific histological pattern involving varying degrees of alveolar wall inflammation or fibrosis, and with a temporal uniformity of lesions. The organized component can be found at different degrees, and the presence of a histologically organized component does not exclude a diagnosis of NSIP. Acute respiratory failure is rare in NSIP. A female patient who presented to our clinic with radiological findings of widespread consolidation and acute respiratory failure was diagnosed with NSIP with organized pneumonia through a surgical lung biopsy. The patient responded rapidly to steroid therapy, and the clinical findings improved dramatically. We present our case in order to emphasize the importance of treatment in the event of respiratory failure in idiopathic NSIP with organized pneumonia, and recommend rapid diagnosis and treatment.

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