Tedaviye Dramatik Yan�t Veren Akut �dyopatik Nonspesifik Pn�moni Olgusu

Gunluoglu, Gulsah; G�nayd�n, Fatma Esra; Urer, Halide Nur; Kalkan, Nurdan; �im�ek Veske, Nurdan; Alt�n, Sedat

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Tedaviye Dramatik Yan�t Veren Akut �dyopatik Nonspesifik Pn�moni Olgusu [Respir Case Rep]

Respir Case Rep. 2019; 8(3): 94-98 | DOI: 10.5505/respircase.2019.52296

Tedaviye Dramatik Yan�t Veren Akut �dyopatik Nonspesifik Pn�moni Olgusu

Gulsah Gunluoglu¹, Fatma Esra G�nayd�n², Halide Nur Urer³, Nurdan Kalkan¹, Nurdan �im�ek Veske¹, Sedat Alt�n¹
¹Sa�l�k Bilimleri �niversitesi, Yedikule G��s Hastal�klar� ve G��s Cerrahisi E�itim ve Ara�t�rma Hastanesi, G��s Hastal�klar� �stanbul
²Uluda� �niversitesi T�p Fak�ltesi, G��s Hastal�klar� Ana Bilim Dal�, Alerji ve Imm�noloji Bilim Dal�, Bursa
³Sa�l�k Bilimleri �niversitesi, Yedikule G��s Hastal�klar� ve G��s Cerrahisi E�itim ve Ara�t�rma Hastanesi, Patoloji, �stanbul

Nonspesifik interstisyel pn�moni (NS�P), idiopatik interstisiyel pn�monilerin bir formudur. Spesifik histolojik paternini, de�i�ken derecelerde alveolar duvar inflamasyonu veya fibrozis e�lik eden temporal uniform lezyonlar olu�turur. Organize komponent de�i�ik derecelerde bulunabilir ve histolojik olarak organize komponentin varl�� NS�P tan�s�n� d��latmaz. Akut solunum yetmezli�i NS�P'te nadir g�r�l�r. Radyolojik olarak yayg�n konsolidasyon bulgular� ve akut solunum yetmezli�i tablosunda klini�imize ba�vuran kad�n hastaya, cerrahi akci�er biyopsisi yap�lm�� ve organize pn�moni komponentli NS�P tan�s� konmu�tur. Steroid tedavisine h�zl� cevap g�zlenmi� ve klinik bulgular dramatik olarak d�zelmi�tir. Organize pn�moni komponentili idiopatik NS�P olgular�n�n solunum yetmezli�i ile ba�vurabileceklerini ve h�zl� tan� ve tedavinin bu hastalardaki �nemini vurgulamak amac�yla olgumuzu sunuyoruz.

Anahtar Kelimeler: NSIP, interstisyel, akut solunum yetmezli�i

A Case of Acute Idiopathic Non-specific Pneumonia with Dramatic Response to Treatment

Gulsah Gunluoglu¹, Fatma Esra G�nayd�n², Halide Nur Urer³, Nurdan Kalkan¹, Nurdan �im�ek Veske¹, Sedat Alt�n¹
¹Health Sciences University, Yedikule Chest Diseases and Chest Surgery Training and Research Hospital,Department of Pulmonary Disease �stanbul
²Uludag University Medical Faculty, Department of Pulmonary Disease, Division of Allergy and Clinical Immunology,Bursa
³Health Sciences University, Yedikule Chest Diseases and Chest Surgery Training and Research Hospital,Department of Pathology �stanbul

Non-specific interstitial pneumonia (NSIP) is a form of idiopathic interstitial pneumonia with a specific histological pattern involving varying degrees of alveolar wall inflammation or fibrosis, and with a temporal uniformity of lesions. The organized component can be found at different degrees, and the presence of a histologically organized component does not exclude a diagnosis of NSIP. Acute respiratory failure is rare in NSIP. A female patient who presented to our clinic with radiological findings of widespread consolidation and acute respiratory failure was diagnosed with NSIP with organized pneumonia through a surgical lung biopsy. The patient responded rapidly to steroid therapy, and the clinical findings improved dramatically. We present our case in order to emphasize the importance of treatment in the event of respiratory failure in idiopathic NSIP with organized pneumonia, and recommend rapid diagnosis and treatment.

Keywords: NSIP, interstitial, acute respiratory failure

Olgunun G�r�nt� Kesitleri

Sorumlu Yazar: Fatma Esra G�nayd�n, T�rkiye
Makale Dili: �ngilizce

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