Penil Sarkoidoz:  Nadir ilk tutulum

Doruk, Sibel; U�an, Ey�p Sabri; Do�an, Faruk; Ta�l�, Funda; Kantarc�, Hasan Umut; Karadeniz, G�listan; Tertemiz, Kemal Can

Cilt : 14 Say� : 2 Y�l : 2025

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Penil Sarkoidoz: Nadir ilk tutulum [Respir Case Rep]

Respir Case Rep. 2016; 5(3): 157-160 | DOI: 10.5505/respircase.2016.53765

Penil Sarkoidoz: Nadir ilk tutulum

Sibel Doruk¹, Ey�p Sabri U�an², Faruk Do�an³, Funda Ta�l�⁴, Hasan Umut Kantarc�⁵, G�listan Karadeniz¹, Kemal Can Tertemiz²
¹�ifa �niversitesi G��s Hastal�klar� Ad., �zmi̇r
²Dokuz Eyl�l �niversitesi G��s Hastal�klar� Ad., �zmi̇r
³�ifa �niversitesi �roloji Ad., �zmi̇r
⁴�ifa �niversitesi Patoloji Ad., �zmi̇r
⁵�ifa �niversitesi Radyoloji Ad., �zmi̇r

Sarkoidozis genito�riner sistemin nadiren tutuldu�u sistemik bir hastal�kt�r ve penis tutulumu ise genito�riner sarkoidoz olgular� aras�nda �ok daha nadir g�r�l�r. Bu makalede penis sarkoidozu tan�s� konulan ve takip edilen iki olgu literat�r e�ili�inde sunulmu�tur. �lk olgu �roloji klini�ine peniste ka��nt� ve a�r� yak�nmas� ile ba�vurmu�tu ve bu yak�nmalar� nonspesifik antibiyotik tedavi ile gerilememi�ti. Biyopside nonkazifiye gran�lomat�z inflamasyon izlendi. Herhangi bir sistemik ve solunumsal yak�nmas� yoktu. Lokal kortikosteroid tedavi verildi. �kinci olgu da �roloji klini�ine peniste nod�l yak�nmas� ile ba�vurmu�tu ve nod�l eksize edilmi�ti. Biyopsi �rne�inde dermisde multinukleer dev h�creler ve gran�lomlar izlendi. Nefes darl��, h�r�lt� ve terleme yak�nmas� olan hastaya sistemik prednizolon tedavisi ba�land�. �ki olgunun da yak�nmalar� uygulanan bu tedaviler ile d�zeldi.

Anahtar Kelimeler: sarkoidoz, genitouriner sarkoidoz, penis sarkoidozu

Penile Sarcoidosis: A Rare Initial Manifestation

Sibel Doruk¹, Ey�p Sabri U�an², Faruk Do�an³, Funda Ta�l�⁴, Hasan Umut Kantarc�⁵, G�listan Karadeniz¹, Kemal Can Tertemiz²
¹Sifa University Department Of Pulmonary Medicine, Izmi̇r
²Dokuz Eylul University Department Of Pulmonary Medicine, Izmi̇r
³Sifa University Department Of Urology, Izmi̇r
⁴Sifa University Department of Pathology, Izmir
⁵Sifa University Department of Radiology, Izmir

Sarcoidosis is a multi-systemic disease and genitourinary involvement is rarely seen. Penile involvement is even rarer among genitourinary sarcoidosis. In this article, we present two cases of penile sarcoidosis. The first case was admitted to our urology clinic with penile itching and pain and his symptoms did not improve with non-specific antibiotic therapy. In biopsy, non-caseified granulomatous inflammation was detected. He did not have any systemic and pulmonary compliant. The second case was admitted to our urology clinic with penile nodules and nodules were excised for diagnosis. In dermis biopsy, multiple multi-nuclear giant cells and granulomas were detected. He had shortness of breath, wheezing, and sweating. He was treated with systemic prednisolone. Both cases were successfully treated with pharmacological treatments.

Keywords: sarcoidosis, genitourinary sarcoidosis, penile sarcoidosis

Sorumlu Yazar: Sibel Doruk, T�rkiye
Makale Dili: �ngilizce

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