Respir Case Rep. 2013; 2(3): 89-94 | DOI: 10.5505/respircase.2013.65365

Kikuchi Fujimoto Hastalýðý: Bir Olgu Nedeniyle

Ayþe Baha¹, Nurdan Köktürk¹, Haluk Türktaþ¹, Nalan Akyürek², Numan Ekim^1
1Gazi Üniversitesi Týp Fakültesi Göðüs Hastalýklarý Anabilim Dalý
²Gazi Üniversitesi Týp Fakültesi Patoloji Anabilim Dalý

Nekrotizan Histiositik Lenfadenit olarak da bilinen Kikuchi Fujimoto Hastalýðý (KFH) özellikle 30 yaþýndan genç kadýnlarda görülen, multipl servikal lenfadenopati ve yüksek ateþ ile seyreden, kendini sýnýrlayan ve 1-4 ayda gerileyen bir klinik tablodur. Sistemik lupus eritamatozis (SLE) ile birlikteliði sýk olarak bildirilir. Bu makalede yüksek ateþ ve öksürük þikayetleri ile tarafýmýza baþvuran ve posteroanterior akciðer grafisinde infiltrasyonlar saptanmasý üzerine pnömoni ön tanýsý ile kliniðimizde takip edilen, fizik muayenede saptanan servikal lenfadenopati biyopsisinde Kikuchi Lenfadeniti saptanan ve romatoloji kliniðince Sjögren Sendromu tanýsý konan 51 yaþýnda kadýn hasta sunulmuþtur. Hastalýðýn daha ileri yaþta saptanmasý, SLE yerine Sjögren Sendromu ve Sjögren Sendromu akciðer tutulumu ile birlikte olmasý gibi özellikli bulgular nedeniyle bu olgu sunulmaya deðer bulunmuþtur.

Anahtar Kelimeler: Kikuchi Fujimoto Hastalýðý, Sjögren Sendromu, akciðer tutulumu

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Kikuchi Fujimoto Disease: A Case Study

Ayþe Baha¹, Nurdan Köktürk¹, Haluk Türktaþ¹, Nalan Akyürek², Numan Ekim^1
1Gazi University Faculty Of Medicine, Department Of Pulmonary Medicine, Ankara, Turkey
²Gazi University Faculty Of Medicine, Department Of Pathology, Ankara, Turkey

Kikuchi Fujimoto Disease (KFD), also known as Necrotizing Histiocytic Lymphadenitis (LAPs), is a clinical entity, which is particularly seen in young women younger than 30 years of age. The disease has a self-limited course that characterized with high fever and multiple lymphadenitis, which resolve within 1 to 4 months. The disease is reported as it is mostly seen in Systemic Lupus Erythematosus (SLE) patients. This study presented a 51-year-old female patient admitted to our clinic with symptoms of fever and cough. The physical examination revealed multiple cervical LAPs and the chest x-ray revealed multilobar infiltration. An excised biopsy of a cervical lymph node revealed the diagnosis of Kikuchi Lymphadenitis. The patient was then diagnosed with Sjögren’s Syndrome and its lung involvement with the appropriate serological markers and clinical picture. Herein, this report was presented to demonstrate that KFD may occur in older ages with Sjögren’s Syndrome and its interstitial lung instead of SLE.

Keywords: Kikuchi Fujimoto Disease, Sjogren Syndrome, pulmonary involvement

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ATIF KOPYALA