Respir Case Rep. 2014; 3(1): 76-79 | DOI: 10.5505/respircase.2014.76598

Küçük hücreli akciðer kanserinin meme metastazý

Nilgün Yýlmaz Demirci¹, Yurdanur Erdoðan¹, Funda Demirað², Aydýn Yýlmaz¹, Ülkü Yýlmaz¹, Çiðdem Biber^1
1Atatürk Göðüs Hastalýklarý ve Göðüs Cerrahisi Eðitim Araþtýrma Hastanesi, Göðüs Hastalýklarý
²Atatürk Göðüs Hastalýklarý ve Göðüs Cerrahisi Eðitim Araþtýrma Hastanesi, Patoloji

Primer meme tümörleri yaygýn olmasýna raðmen memenin metastatik tutulumu nadirdir ve yaklaþýk %1-5 oranýnda görülür. Ellialtý yaþýnda kadýn hasta Temmuz 2009’da nefes darlýðý yakýnmasý ile kliniðimize baþvurdu. Toraks bilgisayarlý tomografisinde (BT) sol hiler kitle mevcuttu. Fiberoptik bronkoskopi ile saptanan endobronþiyal lezyondan alýnan biyopsi sonucu küçük hücreli akciðer karsinomu (KHAK) olarak geldi. Hastaya 4 kür etoposid sisplatin kemoterapisi verildi ve sonrasýnda takibe alýndý. Nisan 2010’da nefes darlýðýnda artýþ yakýnmasý ile tekrar kliniðimize kabul edildi.Yeniden evreleme amaçlý çekilen PET-BT’de sað meme dýþ kadranda 4x3x3 cm ebadýnda SUVmax 13,29 olan artmýþ FGD tutulumu raporlandý. Memedeki lezyondan alýnan biyopsi sonucu KHAK metastazý þeklinde deðerlendirildi. Hastaya 2. basamak VAC (vincristin, adriyamisin, siklofosfamid) kemoterapisi baþlandý. KHAK’nin memeye metastazý nadir olmasý nedeni ile sunuldu.

Anahtar Kelimeler: Meme, metastaz, küçük hücreli akciðer kanseri.

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Small-cell lung cancer metastases in breast

Nilgün Yýlmaz Demirci¹, Yurdanur Erdoðan¹, Funda Demirað², Aydýn Yýlmaz¹, Ülkü Yýlmaz¹, Çiðdem Biber^1
1Atatürk Chest Disease And Chest Surgery Training And Research Hospital, Pulmonary Medicine
²Atatürk Chest Disease And Chest Surgery Training And Research Hospital, Pathology

Although primary breast tumors are quite common, metastatic involvement of all breast masses are rare and account for about 1-5% of cases. A 56-year-old female patient was admitted to our clinic in July 2009 with complaints of shortness of breath. Thoracic computed tomography (CT) scan showed a mass in the left hilar region. Endobronchial lesion was determined by fiberoptic bronchoscopy and the biopsy was evaluated as small cell lung carcinoma. The patient was followed-up after 4 cycles of etoposide + cisplatin chemotherapy. In the follow-up period, due to an increase in shortness of breath the patient was admitted to our clinic again in April 2010. A 4x3x3 cm sized mass in the right upper quadrant of breast lesions obtained for re-staging positron emission tomography (PET-CT) showed intense FDG uptake increase. Needle biopsy of the breast was evaluated as a result of metastasis of small cell lung carcinoma. The patient recieved second-line VAC chemotherapy in April 2010. This case of small-cell lung cancer and breast metastases is presented because of its rarity.

Keywords: Breast, metastasis, small cell lung carcinoma

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