Respir Case Rep. 2012; 1(2): 42-46 | DOI: 10.5505/respircase.2012.87597

Yaygýn kemik metastazý yapmýþ pulmoner karsinoid tümör

Oðuzhan Okutan, Ömer Ayten, Ersin Demirer, Necla Ugan, Zafer Kartaloðlu
GATA Haydarpaþa Eðitim Hastanesi, Göðüs Hastalýklarý, Ýstanbul

Yetmiþ yedi yaþýnda kadýn hasta, üç hafta önce baþlayan sýrt aðrýsý þikayeti ile ortopedi servisine yatýrýldý. Toraks tomografisinde T6 korpusunda ve T7, T8, T12 vertebralarda metastatik lezyonlar ile sað akciðer alt lobda belirgin volüm kaybýna neden olan ve intermedier bronþu oblitere eden en uzun çapý 5.5 cm olan kitlesel lezyon tespit edildi. Fiberoptik bronkoskopide sað intermedier bronþu týkayan endobronþiyal lezyon izlendi. Kitlenin histopatolojik tanýsý karsinoid tümör olarak raporlandý. Kanda ve idrarda serotonin ve 5- hidroksi indol asetik asit seviyeleri normaldi. Torakolomber spinal MR’da medulla spinalis basýsý izlendi. Torakal hemilaminektomi-laminotomi operasyonu uygulandý. T6 vertebra cerrahi rezeksiyon biopsisinin histopatolojik tanýsý atipik karsinoid tümör infiltrasyonu olarak raporlandý. Onkoloji servisine refere edilen hastaya kemoradyoterapi uygulandý.

Anahtar Kelimeler: pulmoner karsinoid tümör, endobronþiyal, metastaz

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Pulmonary carcinoid tumor presenting with widespread bone metastasis

Oðuzhan Okutan, Ömer Ayten, Ersin Demirer, Necla Ugan, Zafer Kartaloðlu
GMMA Haydarpasa Training Hospital, Department Of Pulmonary Medicine, Istanbul

A seventy-seven years old female with a complaining of backache for three weeks was hospitalized in orthopedics clinic. Metastatic lesions at T6 corpus and T7, T8, T12 vertebrae with a mass lesion of 5.5 cm longest diameter obliterating intermediate bronchus leading to volume loss in the right lung lower lobe was observed at thoracal tomography. The endobronchial mass lesion obliterating the right intermediate bronchus was observed in fiberoptic bronchoscopy. The histopathologic diagnosis of the mass was a carcinoid tumor. Levels of serotonin and 5-hydroxy indol acetic acid in blood and urine were normal. Compression to medulla spinalis was observed in MRI of thoracolombar spine. Thoracic hemilaminectomy-laminotomy was performed. The histopathologic diagnosis of surgical resection biopsy of T6 vertebra was reported as the infiltration of atypical carsinoid tumor. The chemoradiotherapy was applied to the patient.

Keywords: pulmonary carcinoid tumor, endobronchial lesion, metastasis

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ATIF KOPYALA