e-ISSN 2147-2475
Cilt : 6 Say : 2 Yl : 2022

Hzl Arama




Laparoscopic Endoscopic Surgical Science Gecikmi tanl paraquat intoksikasyonunda ekstrakorporeal membran oksjenasyonu srasnda direnli hipoksemi [Respir Case Rep]
Respir Case Rep. 2017; 6(2): 118-123 | DOI: 10.5505/respircase.2017.08379

Gecikmi tanl paraquat intoksikasyonunda ekstrakorporeal membran oksjenasyonu srasnda direnli hipoksemi

Nermin Kelebek Girgin, Nurdan nl, Ik enkaya Snak, Remzi imen, Ferda Kahveci, Hadi alayan
Uluda niversitesi Tp Fakltesi, Anesteziyoloji ve Reanimasyon AD

Paraquat, tarmda yaygn kullanlan ve akcierlerde birikimi sonucu ilerleyici pulmoner fibrozise neden olan toksik zellii yksek bir herbisiddir. Paraquat intoksikasyonunda birka gn iinde oklu organ yetmezlii veya birka hafta iinde pulmoner fibrozise bal solunum yetmezlii sonucu lm geliebilir. Veno-venz ekstrakorporeal membran oksijenasyonu(V-V ECMO) gnmzde akut solunum sknts sendromunda(ARDS) yaygn olarak uygulanan bir tedavi stratejisidir. Bu yazda ARDS tans ile yatrlan ve tedavi srecinde V-V ECMO kullanlan bir olguyu sunduk. ECMO desteine ramen yeterli oksijenasyona ulalamayan ve ECMOya bal hipoksi nedenleri dlanan olguda, tekrar sorgulanan tbbi yks sonucu hafta nce paraquata maruziyet olduu saptand. V-V ECMO desteine ramen hipoksi devam eden olgu, youn bakma yatnn 6. gn kaybedildi. Bu olgu aracl ile V-V ECMO srasnda direnli hipoksinin nedenlerini gzden geirmeyi amaladk.

Anahtar Kelimeler: Paraquat intoksikasyonu, ekstrakorporeal membran oksijenasyonu, hipoksemi

Persistent hypoxemia during extracorporeal membrane oxygenation in delayed diagnosed paraquat intoxication

Nermin Kelebek Girgin, Nurdan nl, Ik enkaya Snak, Remzi imen, Ferda Kahveci, Hadi alayan
Uludag University, School of Medicine, Department of Anesthesiology and Reanimation

Paraquat is a highly toxic herbicide used in agriculture worldwide that causes progressive pulmonary fibrosis (PF) due to selective accumulation in the lungs. Paraquat intoxication can result in death due to multi-organ failure within a few days or respiratory failure due to PF within a few weeks. Veno-venous extracorporeal membrane oxygenation (V-V ECMO) is currently a widely used therapeutic strategy for acute respiratory distress syndrome (ARDS). Presently described is case of a 46-year-old man who was hospitalized with ARDS and treated with V-V ECMO. Expected oxygenation levels could not be attained despite ECMO support. When excluding causes for hypoxia in this patient on ECMO, detailed medical history revealed exposure to paraquat 3 weeks previously. Severe hypoxemia persisted during V-V ECMO and the patient died on sixth day after admission. The aim of this study was to examine probable causes of persistent hypoxemia during V-V ECMO observed in this case.

Keywords: Paraquat intoxication, extracorporeal membrane oxygenation, hypoxemia

Nermin Kelebek Girgin, Nurdan nl, Ik enkaya Snak, Remzi imen, Ferda Kahveci, Hadi alayan. Persistent hypoxemia during extracorporeal membrane oxygenation in delayed diagnosed paraquat intoxication. Respir Case Rep. 2017; 6(2): 118-123

Sorumlu Yazar: Nermin Kelebek Girgin, Trkiye
Makale Dili: ngilizce
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