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Laparoscopic Endoscopic Surgical Science Plevral svnn bir nedeni Ailevi Akdeniz Atei [Respir Case Rep]
Respir Case Rep. 2016; 5(3): 184-187 | DOI: 10.5505/respircase.2016.26056

Plevral svnn bir nedeni Ailevi Akdeniz Atei

Efsun Gonca Uur Chousen1, Sinem Karaosman Iliaz2, Hlya Abal1, Sakine ztrk1, Emel alar1
1Yedikule Gs Hastalklar Ve Cerrahisi Eitim Ve Aratrma Hastanesi Istanbul
2Ko niversitesi Tp Fakltesi Gs Hastalklar Departman Istanbul

Krk bir yanda kadn hasta tekrarlayan ate, sol yan ars, nefes darl yaknmalaryla bavurdu. Arka-n akcier grafisinde solda plevral efzyon ile uyumlu grnm saptand. Torasentez ile alnan plevral sv rnekleri eksuda zelliinde olup ntrofil hakimiyeti mevcutu.Hastaya plropnmoni tansyla antibiyoterapi uyguland ve klinik ve ksmi radyolojik iyilemeyle taburcu edildi. hafta sonra ayn ikayetlerle tekrar kliniimize mracaat etti. Hastaya Video Assisted Torakoskopi uyguland. Biyopsi sonucu kronik non-spesifik plrit olarak geldi. Anamnez derinletirildiinde iki ocuunda Ailevi Akdeniz Atei( AAA) olduu ve hastann M680I( G/C) heterojen taycs olduu renildi. Romatoloji blmyle konslte edilerek hastaya oral kolisin 0,5 mg 2x1 baland. Bu tedaviden sonra hastann klinii dzeldi, plevral svs geriledi. AAA tans olan hastalarnn %95 'inde ana yaknma abdominal ardr. Abdominal ar olmakszn plevral ar nadirdir. Plevral sv daha da nadirdir. Plevral efzyonlarn etiyolojisini aratrrken Akdeniz blgesinde yer alan lkemizde, AAAnin de plevral sv nedeni olabileceini aklmzda tutmamz gerekmektedir.

Anahtar Kelimeler: Gs ars, plevral sv, Ailevi Akdeniz Atei

A cause of pleural effusion is Familial Mediterranean Fever

Efsun Gonca Uur Chousen1, Sinem Karaosman Iliaz2, Hlya Abal1, Sakine ztrk1, Emel alar1
1Yedikule Chest Diseases And Thoracic Surgery Education And Research Hospital, Department Of Pulmonary Medicine
2Koc University Hospital, Department Of Pulmonary Medicine

Familial Mediterranean fever (FMF) is an autoinflammatory disease characterized by recurrent abdominal pain and fever episodes. Pleural pain and effusion can also be seen, but rarely in the absence of abdominal pain. FMF is treated with colchicine to control symptoms and to prevent amyloidosis and renal failure. A 41-year-old woman was admitted to our hospital due to recurrent fever, chest pain, and dyspnea. She had an exudative pleural effusion and responded to antibiotic therapy with partial radiographic resolution. She had recurrence of her symptoms three weeks after the completion of therapy. Pleural biopsy by video-assisted thoracoscopy revealed chronic non-specific pleuritis. The patient disclosed that two of her offspring had FMF. Gene analysis showed she was heterozygous carrier of M680I (G/C) mutation. Treatment with colchicine led to resolution of her symptoms and of the pleural effusion. Turkey has a high prevalence of FMF. Pulmonologists should consider FMF in the differential diagnosis of patients with recurrent pleural effusions

Keywords: Chest pain, pleural effusion, Familial Mediterranian Fever

Efsun Gonca Uur Chousen, Sinem Karaosman Iliaz, Hlya Abal, Sakine ztrk, Emel alar. A cause of pleural effusion is Familial Mediterranean Fever. Respir Case Rep. 2016; 5(3): 184-187

Sorumlu Yazar: Efsun Gonca Uur Chousen, Trkiye
Makale Dili: Trke
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