Organize Pn�moni: �� Olgu Sunumu

Do�an, Co�kun; Menek, G�ksel

Cilt : 14 Say� : 1 Y�l : 2025

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Organize Pn�moni: �� Olgu Sunumu [Respir Case Rep]

Respir Case Rep. 2025; 14(1): 27-32 | DOI: 10.5505/respircase.2025.28863

Organize Pn�moni: �� Olgu Sunumu

Co�kun Do�an, G�ksel Menek
�stanbul Medeniyet �niversitesi G��s Hastal�klar� Ana-bilim Dal�, �stanbul, T�rkiye

Histopatolojik tan�m olarak Organize Pn�moni (OP), alveolar alanlar ve bron�iol l�men i�inde fibroblastlar�n, miyofibroblastlar�n ve kollagenin toplanmas� ayn� zamanda proliferasyonu ile karakterize bir akci�er hastal��d�r. OP�ye ba�ta ila� reaksiyonlar�, radyasyon tedavisi gibi etkenler olmak �zere, kollajen vask�ler hastal�klar, enfeksiyonlar gibi bir�ok hastal�k neden olabilir. Radyolojik olarak hava bronkogramlar�n�n e�lik etti�i nod�l veya kitle lezyonlar ile birlikte periferik, yamal� alveolar konsolidasyonlar g�r�lebilir. Her olguda g�r�lmemekle birlikte ters halo i�areti �nemli bir radyolojik bulgudur. Tan�s� klinik-radyolojik ve histopatolojik y�ntemler ile konulur. OP tedavisinde uygun doz ve s�rede kullan�lan glukokortikoid tedaviye yan�tlar� �ok iyidir.

Anahtar Kelimeler: Bron�iolit Obliterans, Organize Pn�moni, Halo ��areti.

Organizing Pneumonia: Three Case Reports

Co�kun Do�an, G�ksel Menek
Department of Pulmonology, �stanbul Medeniyet University Faculty of Medicine, �stanbul, T�rkiye

Organizing pneumonia is characterized histopathologically by the accumulation and proliferation of fibroblasts, myofibroblasts and collagen within the alveolar and bronchiolar lumens, with such potential causes as drug reactions, radiation therapy, collagen vascular diseases and infections. In cases with a specific cause, the condition is referred to as secondary organizing pneumonia, and cryptogenic organizing pneumonia when no cause is apparent. Radiologically, nodules or mass lesions accompanied by air bronchograms may be observed together with patchy peripheral alveolar consolidations. Although not present in every case, the reverse halo sign is an important radiological finding. While clinical-radiological diagnosis is possible, it must be confirmed histopathologically. When steroids appropriate dosages and durations are applied, the results are usually outstanding.

Keywords: Bronchiolitis Obliterans, Organising Pneumonia, Halo Sign.

Sorumlu Yazar: Co�kun Do�an, T�rkiye
Makale Dili: �ngilizce

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