Nefes darlýðý ve ses kýsýklýðýnýn ender bir nedeni: tekrarlayýcý respiratuar papillomatozis

Rekküren respiratuar papillomatozis Human Papilloma Virus'ün neden olduðu nadir bir hastalýktýr. Hastalýk solunum yollarýnda siðil benzeri squamoz lezyonlarla karakterizedir. Sunduðumuz olgu 24 yaþýnda kafkas ýrkýndan bir erkek olup rekküren trakeobronþial papillomatozis saptanmýþtýr. Olguya 1,5 yaþýnda iken laringoskopi yapýlmýþ ve lezyon eksize edilerek taný konulmuþtur. Biyopsi materyali squamoz hücreli papilloma olarak raporlanmýþtýr. Olgu daha önce interferon α-2a ve inhaler interferon tedavisi almýþ fakat semptomlarda duraklama veya gerileme olmamasý nedeniyle sonlandýrýlmýþtý. Hastaya 3 yýldýr her 3 ile 4 ayda bir papilloma eksizyonu yapýlmaktadýr.

An unusual cause of dyspnea and hoarseness: a recurrent respiratory papillomatosis

Recurrent respiratory papillomatosis is a rare respiratory condition associated with human papillomavirus. It is characterized by exophytic, wart-like, squamous lesions within the respiratory tract. Presently described is case of a 24-year-old Caucasian male who presented with recurrent laryngotracheal papillomatosis. Laryngoscopy and excisional biopsy had been performed at approximately 1½ years of age. Biopsy specimen was determined to be squamous cell papilloma. The patient received interferon alpha-2a and inhaled interferon, but treatment was discontinued due to lack of regression or delay in reappearance of symptoms. Rigid bronchoscopy has been performed for recurrent papilloma excision approximately every 3 to 4 months for 3 years.