e-ISSN 2147-2475

Hzl Arama




Akut Masif Pulmoner Embolinin lk Belirtisi Olarak Trombositopeni [Respir Case Rep]
Respir Case Rep. 2021; 10(1): 36-40 | DOI: 10.5505/respircase.2021.36449

Akut Masif Pulmoner Embolinin lk Belirtisi Olarak Trombositopeni

Nai-Chien Huan, Kang Yang Ng, Khai Lip Ng, Jamalul Azizi Abdul Rahaman
Serdang Hastanesi, Gs Hastalklar Blm, Kajang-Malezya

Masif pulmoner emboli (PE) hayat tehdit eden medikal bir durumdur. Bazen, masif PE geiren hastalarda, elik eden bir trombositopeni grlebilir. Sol femurda ar ve hareket kstlna neden olan subperiostal apseli osteomiyeliti bulunan 64 yandaki kadn hasta yatrld. Altta yatan trombofili veya maligniteyi dndren bir bulgusu yoktu. Yatn beinci gnnde, vasopresr destei ve entbasyon gerektiren akut bir solunum sknts ortaya kt. Pulmoner tomografik angiografide, sol inen pulmoner arter ve sol ana pulmoner arterde masif bir pulmoner emboli grld. ncesinde heparin kullanmamasna ramen aklanamayan trombositopeni geliti. Trombolitik tedavi ihtiyac olmasna ramen, bu tedavi kontrendike idi. Multidisipliner bir toplantda cerrahi embolektomi ncesi trombosit saysn dzeltme karar alnd. Ancak hasta iki gn iinde kaybedildi. Aklanamayan bir trombositopeni masif PE iin tek ipucu olabilir. Klinisyenlerin, erken tan ve daha iyi sonular elde etmeleri iin dikkatli olmalar gerekir.

Anahtar Kelimeler: pulmoner emboli, trombositopeni, trombozis

Thrombocytopenia as First Manifestation of Acute Massive Pulmonary Embolism

Nai-Chien Huan, Kang Yang Ng, Khai Lip Ng, Jamalul Azizi Abdul Rahaman
Department of Pulmonology, Serdang Hospital, Kajang, Malaysia

Massive acute pulmonary embolism (PE) is a life-threatening medical condition. Occasionally, patients experiencing a massive PE may develop concurrent thrombocytopenia. A 64-year-old female was admitted for left femur osteomyelitis with a sub-periosteal abscess that was causing pain and immobility. There were no indications suggesting underlying thrombophilia or malignancy. On day 5 of admission, the patient developed acute onset respiratory distress, necessitating intubation and vasopressor support. A computed tomography pulmonary angiogram revealed a massive PE involving the left main trunk and left ascending pulmonary artery. The patient had experienced an unexplained worsening thrombocytopenia that despite without heparin use previously. There was clear indication for thrombolysis, but the treatment was contraindicated. After a multidisciplinary meeting it was decided to optimize platelet counts prior to the performance of a surgical embolectomy, however the patient succumbed 2 days later. The unexplained thrombocytopenia could be the only clue for massive PE. Clinicians should remain vigilant to ensure early diagnosis and improved outcomes.

Keywords: pulmonary embolism, thrombocytopenia, thrombosis

Nai-Chien Huan, Kang Yang Ng, Khai Lip Ng, Jamalul Azizi Abdul Rahaman. Thrombocytopenia as First Manifestation of Acute Massive Pulmonary Embolism. Respir Case Rep. 2021; 10(1): 36-40

Sorumlu Yazar: Nai-Chien Huan, Malaysia
LookUs & Online Makale