Diyet ile Tedavi Edilebilen Hemoptizi: Lane Hamilton Sendromu

Ýdiyopatik pulmoner hemosideroz nadir görülen bir alveolar hemoraji nedenidir ve çölyak hastalýðý ile birlikte görüldüðünde Lane Hamilton Sendromu olarak adlandýrýlýr. Altta yatan neden hala bilinmemekle birlikte, glutensiz diyetle iyileþmeleri ortak bir patogeneze iþaret etmektedir. Tekrarlayan hemoptizi ataklarýyla baþvuran 18 yaþýnda bir kadýn hastaya bronkoskopi yapýlmýþ ve alveolar hemorajiyi doðrulayan hemosiderin yüklü makrofajlar görülmüþtür. Serumda anti-endomisyum IgA varlýðý nedeniyle yapýlan endoskopik biyopsi ile Çölyak Hastalýðý tanýsý doðrulandý. Baþlangýçta glutensiz diyetle semptomlarý dramatik bir þekilde düzelen hasta ilerleyen dönemde diyet uyumsuzluðu nedeniyle alveolar hemoraji ataðýndan kaybedildi.

Diet-treatable Cause of Hemoptysis: Lane Hamilton Syndrome

Idiopathic pulmonary hemosiderosis is a rare cause of alveolar hemorrhage that is referred to as Lane Hamilton Syndrome when co-occurring with coeliac disease. Although the underlying cause is still unknown, the improvements brought by a gluten-free diet point to a shared pathogenesis. An 18-year-old female underwent bronchoscopy after presenting with complaints of recurrent hemoptysis attacks, revealing hemosiderin-laden macrophages pointing to alveolar hemorrhage. The presence of anti-endomysium IgA in the serum, substantiated by an endoscopic biopsy, was indicative of Celiac Disease. Her symptoms improved dramatically upon starting a gluten-free diet, but the patient subse-quently died from an alveolar hemorrhage due to non-compliance with the diet.