Nadir G�r�len Ters Halo ��areti ile Ortaya ��kan Mikroskopik Polianjitis: Olgu Sunumu

Wei, Shengquan; Wang, Huixia; Li, Gen; Lv, Tiantian; Jia, Ruzhen

Cilt : 14 Say� : 2 Y�l : 2025

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Nadir G�r�len Ters Halo ��areti ile Ortaya ��kan Mikroskopik Polianjitis: Olgu Sunumu [Respir Case Rep]

Respir Case Rep. 2025; 14(2): 43-46 | DOI: 10.5505/respircase.2025.92678

Nadir G�r�len Ters Halo ��areti ile Ortaya ��kan Mikroskopik Polianjitis: Olgu Sunumu

Shengquan Wei, Huixia Wang, Gen Li, Tiantian Lv, Ruzhen Jia
Baoji Halk Hastanesi, Yan'an �niversitesi Be�inci Klinik T�p Fak�ltesi, G��s Hastal�klar� Anabilim Dal�, Baoji �ehri, �in

Bu olgu sunumu, akci�er bilgisayarl� tomografisinde ilk olarak ters halo belirisi ile �zde�le�en, mikroskopik poliyanjitis (MPA)'nin nadir bir manifestasyonunu sunmaktad�r. Sensorineural i�itme kayb� ge�mi�i olan 49 ya��ndaki bir kad�n hasta, ilerleyici solunum sistemi semptomlar� nedeniyle kabul edildi. Akci�er tomografisi, laboratuvar testleri ve b�brek biopsisi dahil kapsaml� klinik tetkikler, MPA tan�s�n� do�rulad�. Glukokortikoidler ve siklofosfamid ile hedeflenmi� tedavi, akci�er lezyonlar�ndaki �nemli bir iyile�meye neden oldu. Bu yaz�, klinisyenlerin MPA'n�n atipik sunumuna olan duyarl�l��n� artt�rmak ve potansiyel tan� zorluklar�n� azaltmak amac�yla haz�rlanm��t�r.

Anahtar Kelimeler: Mikroskopik poliyanjitis, Ters halo belirisi, tomografi

Microscopic Polyangiitis Presenting with Uncommon Reversed Halo Sign: A Case Report

Shengquan Wei, Huixia Wang, Gen Li, Tiantian Lv, Ruzhen Jia
Department of Respiratory Medicine, Baoji People's Hospital, the Fifth Clinical Medical College of Yan'an University, Baoji City, China

This case report presents an uncommon manifestation of microscopic polyangiitis (MPA) characterized by an initial reversed halo sign (RHS) on chest computed tomography (CT). A 49-year-old female patient with a history of sensorineural hearing loss presented with progressive respiratory symptoms. Comprehensive clinical investigations, including chest CT, laboratory tests and renal biopsy, confirmed a diagnosis of MPA, and targeted treatment with glucocorticoids and cyclophosphamide resulted in significant improvement in the lung lesions. This report aims to increase clinical awareness of atypical presentations of MPA and to reduce potential diagnostic challenges.

Keywords: Microscopic polyangiitis, Reverse halo sign, tomography

Sorumlu Yazar: Shengquan Wei, China
Makale Dili: �ngilizce

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