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RESPIRATORY CASE REPORTS - Respir Case Rep: 7 (3)
Cilt: 7  Say: 3 - Ekim 2018

OLGU SUNUMU
1.
Tekrarlayan Pnmoni Olarak Yanl Tan Konan ABPA Olgusunda Deien Pulmoner nfiltratlar: Olgu Sunumu ve Literatrn Gzden Geirilmesi
Changing Pulmonary Infiltrates in ABPA Misdiagnosed as Recurrent Pneumonia: A Case Report and Review of the Literature
Shital PATIL, Gajanan Gondhali
doi: 10.5505/respircase.2018.20082  Sayfalar 134 - 139
Pnmoni, Hindistan gibi tropikal lkelerde en sk grlen solunumsal problemdir. Allerjik bronkopulmoner aspergillozis (ABPA), pnmoni ve tberkloz gibi solunumsal hastalklar ile klinik ve radyolojik olarak kartrld iin genellikle tanda ve incelemelerde atlanmaktadr. ABPA, uzun sreli atopik astmal hastalarda Aspergillus antijenine ar duyarllk ile karakterize, aspergillus mantarna ait en iyi tanmlanm bir tablodur. ABPAnn hastaneye yatrlan astmatik hastalarn %20sinde ve tm rinit olgularnn %5inde eitli klinik tablolarla ortaya kt bildirilmitir. Burada, ksrk, ate, nefes darl gibi yaknmalar ile tekrarlayan pnmoni tans ile tedavi edilen, birka yldr astm olduu bilinen orta yal erkek olgu sunulmutur. Bu olguda, sonuta ABPA olarak tan konmu ve sistemik steroid ve antifungal tedavi ile tam klinik ve radyolojik iyileme salanmtr.
Pneumonia is the most common respiratory problem in tropical countries like India. Allergic bronchopulmonary aspergillosis (ABPA) is routinely underdiagnosed and under evaluated as a result of clinical and radiological overlap with many other respiratory conditions, including pneumonia and tuberculosis. ABPA is the best-recognized manifestation of the fungus Aspergillus, associated with hypersensitivity to Aspergillus antigens in patients with longstanding atopic asthma. ABPA has been reported to occur in 20% of asthmatic patients admitted to hospitals and in 5% of all rhinitis cases, with varied clinical presentations. This report is a description of the case of a middle-aged male with known asthma for several years and constitutional symptoms, such as a cough, fever, and shortness of breath, who was diagnosed and treated for recurrent pneumonia. The case was eventually confirmed as ABPA, and a complete clinical and radiological response to medical treatment with antifungals and systemic corticosteroids was documented.

2.
Persistan Trakeo-kutanz Fistl: Olgu Sunumu
Persistent Tracheo-cutaneous Fistula: A Case Report
Rajalakshmi Rajagopalan, Rabeeh Parambil, Krithika Sappavoo, Bharat Shenbagaraj, Siva Ashish, Subramaniam Suriyan, Nagesh Nalini Jayanthi
doi: 10.5505/respircase.2018.50470  Sayfalar 140 - 144
Persistan trakeo-kutanz fistl veya persistan trakeal stoma, trakeostominin ge bir komplikasyonudur. Trakeokutanz fistl, ocuklarda, kanl karldktan sonra trakeostominin spontan kapanmasnn baarsz olmasndan dolay yaygn olarak grlmektedir. Ancak yetikinlerde, bu nispeten daha az yaygndr. Erken ve baarl dekanlasyona ramen akcier tberklozu nedeniyle kalc trakeal stoma ile bavuran 38 yanda bir erkek hastay sunuyoruz.
Persistent tracheo-cutaneous fistula, or persistent tracheal stoma, is a potential late complication of a tracheostomy. It commonly occurs in children due to a failure of spontaneous closure after decannulation. In adults, however, this is relatively less common. Described is a case of a 38-year-old man who, despite undergoing early and successful decannulation, presented with a persistent tracheal stoma due to pulmonary tuberculosis.

3.
akmak Gaz nhalasyonuna Bal Nadir Grlen Diffuz Alveolar Hemoraji Olgusu
A Rare Case of Diffuse Alveolar Hemorrhage Secondary to Lighter Gas Inhalation
Melike Yksel Yavuz, Ceyda Anar, brahim Onur Alc, Filiz Gldaval, Nur Ycel, Melih Bykirin
doi: 10.5505/respircase.2018.94940  Sayfalar 145 - 148
Diffz alveolar hemoraji, etyolojisinde birok nedenin olduu, hemoptizi, anemi, diffz akcier infiltrasyonlar ve solunum yetmezlii ile seyreden hayat tehdit edici bir durumdur. mmn d sebepler arasnda toksik gaz inhalasyonu da vardr. Toksik gazlardan, toplumda uucu madde soluyan kiiler arasnda akmak gaz adyla da bilinen sktrlm btan gaz, bunlardan biridir. Yirmi bir yanda adliyede ktiplik yapan erkek hasta hemoptizi ile bavurdu. Anamnez derinletirildiinde keyif amal akmak gaz soluduu renildi. Hastaya, etyolojisinde bu uucu maddenin rol oynad diffz alveolar hemoraji tans konuldu. akmak gaz inhalasyonunu terk ettikten sonra hemoptizi olmad ve iki ay sonraki toraks bilgisayarl tomografide tama yakn regresyon mevcuttu. Sosyoekonomik durum ayrt etmeden her hastaya madde kullanm sorgulamas yaplmasnn nemini vurgulayan bu olguyu sunmak istedik.
Diffuse alveolar hemorrhage is a life-threatening condition with a varied etiology and one which may be seen with hemoptysis, anemia, diffuse pulmonary infiltrates, or respiratory failure. Toxic gas inhalation is also among the non-immune causes of this disorder. Compressed butane gas, also referred to as lighter gas, is one example, and is a volatile substance inhaled by some individuals as a means to experience euphoria. A 21-year-old male patient, who was a clerk at the courthouse, was admitted with hemoptysis. A detailed history revealed experience breathing lighter gas for pleasure. The patient was diagnosed with diffuse alveolar hemorrhage, and it was concluded that this volatile substance played a role in the etiology of the condition. Hemoptysis was not observed after the patient discontinued lighter gas inhalation and near-total regression was observed in a thorax computed tomography image taken 2 months later. This report is presented to emphasize the importance of inquiring about substance use without regard for the socioeconomic status of the patient.

4.
Kronik Lenfositik Lsemili Bir Olguda Pulmoner Lenfositik nfiltrasyon
Pulmonary Leukaemic Infiltration in Patient with Chronic Lymphocytic Leukaemia
Figen Deveci, Gamze Krkl, Mutlu Kuluztrk, lknur alk, nsel ner
doi: 10.5505/respircase.2018.45712  Sayfalar 149 - 153
Bir aydr nefes darl olan 70 yandaki bayan olgu, nefes darlnda artma yaknmas ile acil servise bavurdu. Fizik muayenesinde bilateral aksiller lenfadenopati saptanan olgunun bir nceki yl Kronik Lenfositik Lsemi (KLL) nedeniyle kemoterapi ald belirlendi. Bilgisayarl toraks tomografisinde hipodens lezyon tespit edildi. Yaplan inceleme sonucunda KLLnin akcier tutulumu (Lenfositik infiltrasyon) saptanan olgu, az grlmesi nedeniyle literatr tartmas eliinde sunuldu.
A 70-year-old woman who had experienced progressive dyspnea for 1 month was admitted to the emergency department. A physical examination revealed bilateral axillary lymphadenopathy and it was determined that she had undergone chemotherapy due to chronic lymphocytic leukemia (CLL) in the previous year. A hypodense lesion was observed on a thorax computed tomography image. The result of the investigation was a determination of pulmonary involvement (lymphocytic infiltration) of CLL. The case is presented in the context of a literature discussion due to the low incidence.

5.
nvazif rotelyal Karsinomlu Hastada Paklitaksele Bal Akcier Toksisitesi
Paclitaxel Associated Lung Toxicity in a Patient with Invasive Urothelial Carcinoma
Merve Erelik, zlem Ataolu, Pnar Yldz Glhan, Fuat Aytekin, Mehmet Fatih Elverili, Onur Ebah, Ege Gle Balbay
doi: 10.5505/respircase.2018.15013  Sayfalar 154 - 157
Paklitaksel, mikrotbl hiperstabilizasyon yoluyla mitotik duraklamay balatan bir anti-kanser ilac olup hidrofobiklii ve hcresel seicilii olmamas nedeniyle yan etkilere neden olmaktadr. Yetmi bir yanda erkek hasta gs hastalklar polikliniine 2 haftadr olan nefes darl ikyeti ile bavurdu. Kasm 2016 da mesane kaynakl invazif rotelyal mesane karsinom tans alan hasta 2 kr Paklitaksel tedavisi almt. Hastann posteroanterior akcier grafisinde bilateral periferik infiltrasyonlar mevcuttu. Yksek Rezolsyonlu Bilgisayarl Tomografide her iki akcierde sada daha belirgin olmak zere periferal-subplevral interlobler septal kalnlamalar, retikler dansiteler, buzlu cam younluk alanlar, periferal yamasal fokal konsolide alanlar izlendi. zellikle her iki alt lob posterobazal segmentlerde periferal yerleimli traksiyon bronektaziler izlendi. Bron lavajnda; hiperplastik rezerv hcreler, makrofajlar, bakteri kmeleri, PNL izlendi, atipik hcre gzlenmedi. Hastada mevcut bulgularla Paklitaksel toksisitesi dnld, kemoterapisi sonlandrld ve metilprednizolon tedavisi baland. Metilprednizolon tedavisinin birinci aynda kontrol akcier grafisinde regresyon izlendi. Paklitaksele bal akcier toksisitesisinin nadir grlmesi nedeniyle bu olguyu sunduk.
Paclitaxel is an anti-cancer drug that induces mitotic arrest via microtubule hyperstabilization, but which also causes side effects due to its hydrophobicity and cellular promiscuity. A 71-year-old male patient presented at the polyclinic with dyspnea present for 2 weeks. In November 2016, the patient had been diagnosed with bladder-derived invasive urothelial bladder carcinoma and received 2 cycles of paclitaxel therapy. High-resolution computed tomography revealed peripheral-subpleural interlobular septal thickening, reticular densities, ground-glass density areas, and peripheral focal consolidation in both lungs, particularly on the right. Peripheral traction bronchiectasis was also observed, especially in the posterobasal segments of both lower lobes. Bronchial lavage revealed hyperplastic reserve cells, macrophages, bacterial clusters, and polymorphonuclear leukocytes, but no atypical cell were observed. The infection was ruled out. Chemotherapy was terminated and methylprednisolone (0.75 mg/kg) was initiated. Regression was observed in a control posteroanterior chest graphy after 1 month of steroid therapy. This case was presented because lung toxicity due to paclitaxel is rare.

6.
Slfasalazin'e Bal Gelien Eozinofilik Pnmoni
Sulfasalazine Induced Eosinophilic Pneumonia
Selma Aydoan Erolu, Hakan Gnen, Halil brahim Yakar, Dildar Duman
doi: 10.5505/respircase.2018.93764  Sayfalar 158 - 161
Eozinofilik akcier hastalklar, artm kan veya doku eozinofilisi ile birlikte seyreden hastalklarn oluturduu geni bir gruptur. laca bal eozinofilik pnmoni, pulmoner infiltratlarla birlikte kan veya doku eozinofilisiyle seyreden bir durumdur. Yirmi sekiz yanda kadn hasta, 3 haftadan beri balayan ate, me ve ksrk ikyetiyle polikliniimize bavurdu. Daha nce pnmoni tansyla 15 gn antibiyoterapi alm ve ikyetlerinde deiiklik olmamt. zgemiinde sacroileit nedeniyle slfasalazin kullanm mevcuttu. Romatoloji tarafndan tetkik edilip baka bir sistemik hastalk saptanmamt. Akcier grafisinde bilateral periferik subplevral opasiteler, kan saymnda lkositozu ve eozinofilisi mevcuttu. Toraks bilgisayarl tomografide bilateral periferik buzlu cam dansitesinde opasiteler, septal kalnlamalar ve retikler dansiteler saptand. Eozinofilisi olmas, antibiyoterapiye yant vermemesi, baka sistemik hastal olmamas nedeniyle bulgularnn slfasalazin kullanmna bal olabilecei dnld. Slfasalazin kesilip prednizolon tedavisi balanld. Hastann semptomlar dramatik bir ekilde dzeldi. Kan tablosu dzeldi. Radyolojik olarak tam regresyon izlendi. Olgumuz slfasalazin kullanmna bal gelien eozinofilik pnmoni tablosudur. la yksnn her pulmoner deerlendirmede dikkatle ele alnmas nemlidir.
Eosinophilic lung disease encompasses a large group of diseases caused by increased blood or tissue eosinophilia. Eosinophilic pneumonia due to prescription drug use is a condition in which pulmonary infiltrates with blood or tissue eosinophilia are seen. A 28-year-old female patient admitted to the outpatient clinic with complaints of fever, chills, and a cough of 3 weeks duration. She had been taking antibiotics for 15 days with a diagnosis of pneumonia, but her complaints did not change. Her history revealed the use of sulfasalazine due to sacroiliitis. A rheumatology examination detected no other rheumatic disease. A posteroanterior chest X-ray showed bilateral peripheral opacities. A peripheral blood count revealed leukocytosis and eosinophilia. A thoracic computed tomography image revealed bilateral peripheral ground glass opacities, septal thickening, and reticular densities. Based on the findings of eosinophilia, no response to antibiotics, and no other systemic disease, it was considered that the condition might be related to the use of sulfasalazine. Sulfasalazine was discontinued and prednisolone therapy was started. The patient's symptoms improved dramatically, and the abnormal blood values returned to normal. Radiologically, complete regression was observed. This was a case of eosinophilic pneumonia due to the use of sulfasalazine. It is important that drug history is handled carefully in every pulmonary evaluation.

7.
Sertralin ilikili akcier hastal
Sertraline Related Pulmonary Disease
Fatih Uzer, Aliye Candan
doi: 10.5505/respircase.2018.49344  Sayfalar 162 - 165
nterstisyel akcier hastalklarnn % 2,5-3nn ilalarla ilikili olarak ortaya kt bildirilmektedir. lalar, solunum sisteminin tm komponentlerinde, yan etkileri gsterebilmektedirler. Altm sekiz yanda kadn hasta 2 haftadr olan ksrk ve ate yaknmalar ile solunum hastalklar polikliniine bavurdu. Fizik muayenesinde, solunum sisteminde bilateral alt zonlarda raller duyuldu. zgemiinde depresyon nedeniyle sertralin kullanma yks vard. Yaplan klinik deerlendirme, radyolojik grntleme ve laboratuvar neticelerin sonunda hastaya ilalara bal interstisyel akcier hastal tans kondu. lalara bal interstisyel akcier hastalklar nadir grldnden literatre katk salamak amacyla olguyu sunuyoruz.
It has been reported that 2.5% to 3% of interstitial lung diseases are related to prescription drugs. Drugs can demonstrate side effects in all components of the respiratory system. A 68-year-old woman was admitted to the department of respiratory diseases with a history of a cough and fever present for 2 weeks. A physical examination revealed crackles in the bilateral lower zones of the respiratory system. She had a history of using sertraline for depression. Based on the results of the clinical evaluation, radiological imaging, and laboratory findings, the patient was diagnosed with interstitial pulmonary disease emerging as a side effect of prescription drug use. As drug-related interstitial lung disease is rare, this case is presented as a contribution to the literature.

8.
Pulmoner Tromboembolinin Nadir Bir Nedeni Olarak Faktr VII Eksiklii
Factor VII Deficiency as a Rare Cause of Pulmonary Thromboembolism
Fatih Uzer, Tlay zdemir
doi: 10.5505/respircase.2018.30085  Sayfalar 166 - 168
Kaltsal faktr VII eksiklii, nadir grlmesine ramen, kaltsal faktr eksiklikleri iinde en fazla otozomal resesif gei gsteren bir hastalktr. Asemptomatik olabildii gibi, ounlukla mukoza kanamas, eklem ve kas ii kanama, intrakraniyal kanama gibi kanama diatezi bulgular ile seyredebilir. te yandan ok ender olarak bu hastalarda arteriyel veya venz tromboz bildirilmitir. Kliniimizde pulmoner tromboemboli tans alan bir kaltsal faktr VII eksiklii tanl olguyu sunuyoruz.
Hereditary factor VII deficiency is rare recessive autosomal disorder. It may be asymptomatic and typically presents with signs of bleeding diathesis, such as mucosal bleeding, joint and muscle hemorrhage, or intracranial hemorrhage; arterial and venous thrombosis is rare in the literature. Presently described is a case of a patient who had hereditary factor VII deficiency diagnosed with pulmonary thromboembolism.

9.
Konjenital Lober Amfizem: ki Olgu Sunumu
Congenital Lobar Emphysema: Report of Two Cases
Fatih Meterolu, Atalay ahin, Menduh Oru
doi: 10.5505/respircase.2018.33154  Sayfalar 169 - 172
Konjenital lober amfizem; akcierin bir veya daha fazla lobunun hiperekspansiyonu, bunun evredeki normal akcier dokusuna bass ve mediastinal kayma ile karakterli bir respiratuvar distres nedenidir. Yeni doan dneminde solunum skntsna yol amakla birlikte, ender olarak semptomlarn ortaya k altnc aya kadar gecikebilir. Nadir grlen bir hastalktr. Spontan pnmotoraks ile kartrlmas ve ciddi olgularda uygulanan acil cerrahi mdahale ile klinik tablonun dramatik olarak dzelmesi nedeniyle nem tamaktadr. Kliniimizde solunum sknts, sk sk enfeksiyon nedeniyle medikal tedavi alan 4 ve 27 aylk iki erkek olgu yatrld. Her iki olguya da lober amfizem nedeniyle sol st lobektomi yapld. Cerrahi ilem sonras takiplerinde genel durumlarnda ve solunum dzeylerinde ciddi dzelmeler olan iki olguyu sunmay amaladk.
Congenital lobar emphysema is a cause of respiratory distress characterized by hyperexpansion of 1 or more lobes of the lung, compression onto the ipsilateral or contralateral functional pulmonary parenchymas, and a resultant mediastinal shift. The onset of symptoms may be delayed until the age of 6 months, although the disease causes dyspnea in newborns or infancy. It is a rarely seen disease. Awareness is important due to confusion with pneumothorax and the possibility of considerable clinical improvement with early surgical intervention, even in severe cases. Two male patients with failed conservative treatment, 4 and 27 months of age, were hospitalized in this clinic because of respiratory distress and repeated infections. A left upper lobectomy was performed due to lobar emphysema in both patients. The goal of this report was to present the improvement in respiratory function and general condition of 2 patients observed after surgical management.

EDITRE MEKTUP
10.
Rosai-Dorfman Hastalnda Akcier Tutulumu
Rosai-Dorfman Disease with Involvement of the Lungs
Esra Karaku, Aye Selcen Ouz Erdoan, Derya zyrk, Glah Bayram
doi: 10.5505/respircase.2018.26879  Sayfalar 173 - 174
Makale zeti | Tam Metin PDF

YAZAR NDEKSI
11.
Yazar ndeksi
Author Index

Sayfalar 175 - 176
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HAKEM NDEKSI
12.
Hakem ndeksi
Reviewer Index

Sayfa 177
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